Department of Maternal and Child Health, School of Public Health, Peking University, Beijing, China.
Department of Fitness Surveillance Centre, China Institute of Sport Science, Beijing, China.
PLoS One. 2021 Oct 28;16(10):e0258763. doi: 10.1371/journal.pone.0258763. eCollection 2021.
This study aimed to identify the 15-year trends of handgrip strength-to-weight (relative HS) and assess the association between relative HS and hypertension among Chinese adults aged 20-69.
Using a complex, stratified, multistage probability cluster sampling, we analyzed data collected from 712,442 adults aged 20-69 years in four successive national surveys (2000-2014). We used a handheld dynamometer to measure strength and divided by body weight to calculate the relative HS. Blood pressure was recorded with a sphygmomanometer and hypertension was defined as resting systolic blood pressure at least 140 mmHg or diastolic at least 90 mmHg. The Mann-Kendall trend test examined trends in relative HS over time. We also computed odd ratios (OR) and 95% confidence intervals (95% CI) by tertile of relative HS and examined the association between relative HS and hypertension.
The relative HS level decreased with the increase of age in both male and females (p trend <0.001). In each of four surveys, one interquartile decrease in relative HS was associated with an increased risk of hypertension by 44% (OR = 1.44, 95%CI: 1.40-1.47), 58% (OR = 1.58, 95%CI: 1.54-1.62), 48% (OR = 1.48, 95%CI: 1.45-1.52), 43% (OR = 1.43, 95%CI: 1.40-1.47), respectively.
In the Chinese adult population, the relative HS level decreased from 2000 to 2014 across all ages in both males and females. A lower relative HS was associated with a higher risk of hypertension. The findings provided evidence for the association between muscle strength and hypertension in large-scaled population.
本研究旨在确定握力与体重比（相对 HS）的 15 年趋势，并评估中国 20-69 岁成年人相对 HS 与高血压之间的关系。
我们采用复杂的、分层的、多阶段概率聚类抽样方法，分析了 712442 名 20-69 岁成年人在四次连续全国调查（2000-2014 年）中的数据。我们使用手持式测力计测量力量，并将其除以体重以计算相对 HS。使用血压计记录血压，将静息收缩压至少 140mmHg 或舒张压至少 90mmHg 定义为高血压。Mann-Kendall 趋势检验用于检测相对 HS 随时间的变化趋势。我们还根据相对 HS 的三分位数计算比值比（OR）和 95%置信区间（95%CI），并检查相对 HS 与高血压之间的关系。
在男性和女性中，相对 HS 水平随年龄的增加而降低（趋势检验<0.001）。在四次调查中的每一次，相对 HS 每降低一个四分位距，高血压的风险增加 44%（OR=1.44，95%CI：1.40-1.47）、58%（OR=1.58，95%CI：1.54-1.62）、48%（OR=1.48，95%CI：1.45-1.52）、43%（OR=1.43，95%CI：1.40-1.47）。
在中国成年人群体中，男性和女性的所有年龄段的相对 HS 水平从 2000 年到 2014 年都有所下降。较低的相对 HS 与高血压的风险增加有关。这些发现为肌肉力量与高血压之间的关联提供了大型人群研究的证据。
