Tsai Szu-Ying, Huang Wei-Hsin, Chan Hsin-Lung, Hwang Lee-Ching
Department of Family Medicine, Mackay Memorial Hospital, Taipei City, Taiwan.
Department of Family Medicine, Taipei City Hospital, Zhongxing Branch, Taipei City, Taiwan.
Tob Induc Dis. 2021 Oct 22;19:82. doi: 10.18332/tid/142664. eCollection 2021.
Cigarette smoking affects blood pressure and is a major risk factor for cardiovascular diseases. The role of smoking cessation programs with respect to blood pressure remains inconclusive. Thus, this study aimed to investigate the effects of a smoking cessation program on blood pressure.
Participants who attended the smoking cessation program in an outpatient clinic of a tertiary medical center in Taiwan from 2017 to 2018 were enrolled in this retrospective cohort study. Their smoking cessation status was traced via phone calls during the third month, and the researchers collected participant characteristics and blood pressure before and after the program. Differences in the participants' blood pressure, based on those with and those without hypertension, were compared using analysis of covariance. Univariable logistic regression models were used to determine factors associated with success in smoking cessation. In total, there were 721 participants. The participants had a mean age of 55.8±11.4 years and 68.1% of the participants were hypertensive.
During the program, the overall systolic blood pressure decreased by 4.0±17.9 mmHg and diastolic blood pressure decreased by 2.5±12.0 mmHg, from the baseline. Hypertensive participants showed a more prominent blood pressure lowering effect compared to non-hypertensive participants in terms of the subtraction difference of systolic blood pressure (-5.0±19.0 vs -1.9±15.2 mmHg, p=0.018) and diastolic blood pressure (-3.1±12.9 vs -1.1±9.6 mmHg, p=0.016). After multivariate control, the results showed that the adjusted subtraction difference of diastolic blood pressure was still more significant in the hypertensive group than in the non-hypertensive group.
The smoking cessation program significantly reduced both systolic blood pressure and diastolic blood pressure in the entire cohort. The results were more significant in the hypertensive group compared to the non-hypertensive group.
吸烟会影响血压，是心血管疾病的主要危险因素。戒烟计划对血压的作用仍无定论。因此，本研究旨在探讨戒烟计划对血压的影响。
本回顾性队列研究纳入了2017年至2018年在台湾一家三级医疗中心门诊参加戒烟计划的参与者。在第三个月通过电话追踪他们的戒烟状态，研究人员收集了参与者的特征以及计划前后的血压。使用协方差分析比较了有高血压和无高血压参与者的血压差异。采用单变量逻辑回归模型确定与戒烟成功相关的因素。共有721名参与者。参与者的平均年龄为55.8±11.4岁，68.1%的参与者患有高血压。
在计划期间，收缩压总体较基线下降了4.0±17.9 mmHg，舒张压下降了2.5±12.0 mmHg。就收缩压的差值而言（-5.0±19.0 vs -1.9±15.2 mmHg，p = 0.018）以及舒张压的差值而言（-3.1±12.9 vs -1.1±9.6 mmHg，p = 0.016），高血压参与者的血压降低效果比非高血压参与者更为显著。多变量控制后，结果显示高血压组舒张压调整后的差值仍比非高血压组更显著。
戒烟计划使整个队列的收缩压和舒张压均显著降低。与非高血压组相比，高血压组的结果更为显著。
