Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials.

Control of denture plaque biofilms is a practical approach to preventing persistent oral infections such as denture stomatitis. . This study compared biofilm attachment and growth on a new denture material, Ultaire® AKP, with that on traditional denture materials including cobalt chrome (CoCr), polymethyl methacrylate (PMMA), and polyoxymethylene (POM). . Microbial biofilms were grown with cultures of , UA159, or a mixed spp. ( 700610/ BAA-1455) for 6 hours in a static protocol or 24 hours in a dynamic protocol for each material. Adherent biofilm cells were removed, and viable colony-forming units (CFUs) were enumerated. Confocal microscopy of the 24-hour spp. biofilms was used to determine biofilm mass and roughness coefficients. . The rank order of attachment after 6 hours was CoCr > PMMA  > Ultaire® AKP ( vs CoCr, ≤ 0.05), and that for 24-hour biofilm growth was CoCr > Ultaire® AKP  > PMMA ( vs CoCr, ≤ 0.05). The rank order of biofilm attachment was CoCr > POM > Ultaire® AKP  > PMMA ( vs CoCr, ≤ 0.05), and that for the 24-hour spp. biofilm growth was POM > Ultaire® AKP > PMMA > CoCr ( vs POM, ≤ 0.05). Confocal images revealed structural differences in spp. biofilms on CoCr compared with the other test materials. Significantly lower roughness coefficients of spp. biofilms on Ultaire® AKP were noted, suggesting that these biofilms were less differentiated. Ultaire® AKP promoted significantly less and biofilm attachment than CoCr at 6 hours and growth at 24 hours. spp. biofilms on Ultaire® AKP were less differentiated than those on other test materials. . In addition to its material strength, Ultaire® AKP represents an attractive option for denture material in removable partial dentures.