• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

败血症。

Sepsis.

机构信息

Masters in Healthcare Innovation Program, The Ohio State University, Columbus, OH, USA.

Viven Health, 006 Woodbridge Creek Court, St Louis, MO 63129, USA.

出版信息

Crit Care Nurs Clin North Am. 2021 Dec;33(4):407-418. doi: 10.1016/j.cnc.2021.08.003. Epub 2021 Oct 9.

DOI:10.1016/j.cnc.2021.08.003
PMID:34742497
Abstract

This article provides an overview of the history of the sepsis definitions as well as an overview of the current understanding of the pathogenesis of sepsis. The evolution of the treatment bundles is also presented.

摘要

本文概述了脓毒症定义的历史，以及对脓毒症发病机制的当前理解，并介绍了治疗方案的演变。

相似文献

1
Sepsis.败血症。
Crit Care Nurs Clin North Am. 2021 Dec;33(4):407-418. doi: 10.1016/j.cnc.2021.08.003. Epub 2021 Oct 9.
2
Low sensitivity of qSOFA, SIRS criteria and sepsis definition to identify infected patients at risk of complication in the prehospital setting and at the emergency department triage.qSOFA、SIRS 标准和脓毒症定义对识别院前环境和急诊科分诊中感染风险患者的并发症的敏感性较低。
Scand J Trauma Resusc Emerg Med. 2017 Nov 3;25(1):108. doi: 10.1186/s13049-017-0449-y.
3
Systemic Inflammatory Response Syndrome, Quick Sequential Organ Function Assessment, and Organ Dysfunction: Insights From a Prospective Database of ED Patients With Infection.全身炎症反应综合征、快速序贯器官功能评估与器官功能障碍：来自急诊感染患者前瞻性数据库的见解
Chest. 2017 Mar;151(3):586-596. doi: 10.1016/j.chest.2016.10.057. Epub 2016 Nov 19.
4
Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit.qSOFA与SIRS用于预测非重症监护病房疑似脓毒症患者不良结局的比较。
Crit Care. 2017 Mar 26;21(1):73. doi: 10.1186/s13054-017-1658-5.
5
The Combined SIRS + qSOFA (qSIRS) Score is More Accurate Than qSOFA Alone in Predicting Mortality in Patients with Surgical Sepsis in an LMIC Emergency Department.联合 SIRS + qSOFA（qSIRS）评分比单独 qSOFA 更能准确预测中低收入国家急诊外科脓毒症患者的死亡率。
World J Surg. 2020 Jan;44(1):21-29. doi: 10.1007/s00268-019-05181-x.
6
Usefulness of qSOFA and SIRS scores for detection of incipient sepsis in general ward patients: A prospective cohort study.qSOFA 和 SIRS 评分对普通病房患者早期脓毒症检测的有用性：一项前瞻性队列研究。
J Crit Care. 2019 Jun;51:13-18. doi: 10.1016/j.jcrc.2019.01.012. Epub 2019 Jan 18.
7
Using sepsis scores in emergency department and ward patients.在急诊科和病房患者中使用脓毒症评分。
Br J Hosp Med (Lond). 2019 Aug 2;80(8):C120-C123. doi: 10.12968/hmed.2019.80.8.C120.
8
SIRS or qSOFA? Is that the question? Clinical and methodological observations from a meta-analysis and critical review on the prognostication of patients with suspected sepsis outside the ICU.全身炎症反应综合征（SIRS）还是快速序贯器官功能衰竭评估（qSOFA）？这是问题所在吗？一项关于 ICU 外疑似脓毒症患者预后预测的荟萃分析和批判性评价的临床和方法学观察。
Intern Emerg Med. 2019 Jun;14(4):593-602. doi: 10.1007/s11739-018-1965-0. Epub 2018 Oct 15.
9
[New Sepsis-3 definition : Do we have to treat sepsis before we can diagnose it from now on?].[新的脓毒症-3定义：从现在起，我们必须在诊断脓毒症之前就进行治疗吗？]
Anaesthesist. 2017 Aug;66(8):614-621. doi: 10.1007/s00101-017-0316-2.
10
Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).脓毒症临床标准评估：针对《脓毒症及脓毒性休克第三次国际共识定义》（Sepsis-3）。
JAMA. 2016 Feb 23;315(8):762-74. doi: 10.1001/jama.2016.0288.

引用本文的文献

1
Immune Dysregulation and Prognosis in Sepsis: Insights From a Posttranslational Perspective.脓毒症中的免疫失调与预后：从翻译后角度的见解
Hum Mutat. 2025 Jul 8;2025:5503939. doi: 10.1155/humu/5503939. eCollection 2025.
2
The impact of sedation and analgesia scores on prognosis in critically ill sepsis patients with sepsis-associated encephalopathy: a retrospective analysis.镇静和镇痛评分对伴有脓毒症相关性脑病的重症脓毒症患者预后的影响：一项回顾性分析
Front Neurol. 2025 Jun 25;16:1622964. doi: 10.3389/fneur.2025.1622964. eCollection 2025.
3
Advancements, Challenges, and Future Prospects of Nanotechnology in Sepsis Therapy.
纳米技术在脓毒症治疗中的进展、挑战与未来前景
Int J Nanomedicine. 2025 Jun 16;20:7685-7714. doi: 10.2147/IJN.S488026. eCollection 2025.
4
Optimization of meropenem dosing regimens in critically ill patients with augmented renal clearance.重症患者肾清除率增加时美罗培南给药方案的优化
Front Med (Lausanne). 2025 May 9;12:1550053. doi: 10.3389/fmed.2025.1550053. eCollection 2025.
5
Comprehending toll-like receptors: pivotal element in the pathogenesis of sepsis and its complications.理解 Toll 样受体：脓毒症及其并发症发病机制中的关键要素。
Front Immunol. 2025 May 2;16:1591011. doi: 10.3389/fimmu.2025.1591011. eCollection 2025.
6
The predictive value of renal vascular resistance index and serum biomarkers for sepsis-associated acute kidney injury: a retrospective study.肾血管阻力指数和血清生物标志物对脓毒症相关急性肾损伤的预测价值：一项回顾性研究。
BMC Nephrol. 2025 Apr 25;26(1):208. doi: 10.1186/s12882-025-04131-1.
7
The critical immunoregulatory roles and molecular mechanisms of IL-10 and IL-18 genes in pneumonia and sepsis.白细胞介素-10和白细胞介素-18基因在肺炎和脓毒症中的关键免疫调节作用及分子机制
Medicine (Baltimore). 2025 Apr 18;104(16):e42104. doi: 10.1097/MD.0000000000042104.
8
Inhibition of neutrophil extracellular traps alleviates blood-brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy.抑制中性粒细胞胞外诱捕网通过Wnt3/β-连环蛋白/TCF4信号通路减轻脓毒症相关性脑病中的血脑屏障破坏和认知功能障碍。
J Neuroinflammation. 2025 Mar 18;22(1):87. doi: 10.1186/s12974-025-03395-6.
9
Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning models.通过基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）和基于树的机器学习模型快速检测阳性血培养物中的耐碳青霉烯类大肠杆菌和耐碳青霉烯类肺炎克雷伯菌
BMC Microbiol. 2025 Jan 24;25(1):44. doi: 10.1186/s12866-025-03755-5.
10
Utilizing integrated bioinformatics and machine learning approaches to elucidate biomarkers linking sepsis to purine metabolism-associated genes.利用综合生物信息学和机器学习方法来阐明将脓毒症与嘌呤代谢相关基因联系起来的生物标志物。
Sci Rep. 2025 Jan 2;15(1):353. doi: 10.1038/s41598-024-82998-0.