Ding Weiping, Abdel-Basset Mohamed, Hawash Hossam, ELkomy Osama M
IEEE Trans Cybern. 2023 Feb;53(2):1285-1298. doi: 10.1109/TCYB.2021.3123173. Epub 2023 Jan 13.
The localization and segmentation of the novel coronavirus disease of 2019 (COVID-19) lesions from computerized tomography (CT) scans are of great significance for developing an efficient computer-aided diagnosis system. Deep learning (DL) has emerged as one of the best choices for developing such a system. However, several challenges limit the efficiency of DL approaches, including data heterogeneity, considerable variety in the shape and size of the lesions, lesion imbalance, and scarce annotation. In this article, a novel multitask regression network for segmenting COVID-19 lesions is proposed to address these challenges. We name the framework MT-nCov-Net. We formulate lesion segmentation as a multitask shape regression problem that enables partaking the poor-, intermediate-, and high-quality features between various tasks. A multiscale feature learning (MFL) module is presented to capture the multiscale semantic information, which helps to efficiently learn small and large lesion features while reducing the semantic gap between different scale representations. In addition, a fine-grained lesion localization (FLL) module is introduced to detect infection lesions using an adaptive dual-attention mechanism. The generated location map and the fused multiscale representations are subsequently passed to the lesion regression (LR) module to segment the infection lesions. MT-nCov-Net enables learning complete lesion properties to accurately segment the COVID-19 lesion by regressing its shape. MT-nCov-Net is experimentally evaluated on two public multisource datasets, and the overall performance validates its superiority over the current cutting-edge approaches and demonstrates its effectiveness in tackling the problems facing the diagnosis of COVID-19.
从计算机断层扫描(CT)图像中对2019年新型冠状病毒病(COVID-19)病变进行定位和分割,对于开发高效的计算机辅助诊断系统具有重要意义。深度学习(DL)已成为开发此类系统的最佳选择之一。然而,一些挑战限制了DL方法的效率,包括数据异质性、病变形状和大小的显著差异、病变不平衡以及标注稀缺。在本文中,提出了一种用于分割COVID-19病变的新型多任务回归网络来应对这些挑战。我们将该框架命名为MT-nCov-Net。我们将病变分割表述为一个多任务形状回归问题,该问题能够利用不同任务之间的低质量、中等质量和高质量特征。提出了一种多尺度特征学习(MFL)模块来捕获多尺度语义信息,这有助于在减少不同尺度表示之间语义差距的同时,高效地学习小病变和大病变特征。此外,引入了一个细粒度病变定位(FLL)模块,使用自适应双注意力机制来检测感染病变。生成的位置图和融合的多尺度表示随后被传递到病变回归(LR)模块以分割感染病变。MT-nCov-Net能够通过回归COVID-19病变的形状来学习完整的病变属性,从而准确地分割病变。在两个公共多源数据集上对MT-nCov-Net进行了实验评估,整体性能验证了其优于当前前沿方法,并证明了其在解决COVID-19诊断面临的问题方面的有效性。