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Asthma and Obstructive Sleep Apnea Overlap: What Has the Evidence Taught Us?哮喘与阻塞性睡眠呼吸暂停重叠:证据告诉了我们什么?
Am J Respir Crit Care Med. 2020 Jun 1;201(11):1345-1357. doi: 10.1164/rccm.201810-1838TR.
2
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Eur Respir Rev. 2019 Oct 9;28(153). doi: 10.1183/16000617.0080-2019. Print 2019 Sep 30.
3
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Cohort profile: the West Sweden Asthma Study (WSAS): a multidisciplinary population-based longitudinal study of asthma, allergy and respiratory conditions in adults.队列研究简介:瑞典西部哮喘研究(WSAS):一项多学科、基于人群的成人哮喘、过敏和呼吸道疾病的纵向研究。
BMJ Open. 2019 Jun 19;9(6):e027808. doi: 10.1136/bmjopen-2018-027808.
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Apneic Sleep, Insufficient Sleep, and Hypertension.呼吸暂停性睡眠、睡眠不足与高血压。
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Asthma and COPD overlap (ACO) is related to a high burden of sleep disturbance and respiratory symptoms: Results from the RHINE and Swedish GA2LEN surveys.哮喘和慢性阻塞性肺疾病重叠(ACO)与睡眠障碍和呼吸系统症状负担高有关:来自 RHINE 和瑞典 GA2LEN 调查的结果。
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Sleep. 2018 Mar 1;41(3). doi: 10.1093/sleep/zsx214.

打鼾和失眠并存对健康的负面影响。

The negative health effects of having a combination of snoring and insomnia.

机构信息

Department of Medical Sciences, Respiratory, Allergy, and Sleep Research, Uppsala University, Uppsala, Sweden.

Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.

出版信息

J Clin Sleep Med. 2022 Apr 1;18(4):973-981. doi: 10.5664/jcsm.9764.

DOI:10.5664/jcsm.9764
PMID:34753555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8974365/
Abstract

STUDY OBJECTIVES

Insomnia and snoring are common sleep disorders. The aim was to investigate the association of having a combination of insomnia symptoms and snoring with comorbidity and daytime sleepiness.

METHODS

The study population comprised 25,901 participants (16-75 years, 54.4% women) from 4 Swedish cities, who answered a postal questionnaire that contained questions on snoring, insomnia symptoms (difficulties initiating and/or maintaining sleep and/or early morning awakening), smoking, educational level, and respiratory and nonrespiratory disorders.

RESULTS

Snoring was reported by 4,221 (16.2%), while 9,872 (38.1%) reported ≥ 1 insomnia symptom. A total of 2,150 (8.3%) participants reported both insomnia symptoms and snoring. The association with hypertension (adjusted odds ratio [OR], 1.4; 95% confidence interval [CI], 1.2-1.6), chronic obstructive pulmonary disease (adjusted OR, 1.8; 95% CI, 1.3-2.4), asthma (adjusted OR, 1.9; 95% CI, 1.6-2.3), daytime sleepiness (adjusted OR, 7.9; 95% CI, 7.1-8.8), and the use of hypnotics (adjusted OR, 7.5; 95% CI, 6.1-9.1) was highest for the group with both insomnia symptoms and snoring.

CONCLUSIONS

Participants with both snoring and insomnia run an increased risk of hypertension, chronic obstructive pulmonary disease, asthma, daytime sleepiness, and use of hypnotics. It is important to consider snoring in patients seeking medical assistance for insomnia and, vice versa, in patients with snoring inquiring about insomnia.

CITATION

Hägg SA, Ilieva E, Ljunggren M, et al. The negative health effects of having a combination of snoring and insomnia. . 2022;18(4):973-981.

摘要

研究目的

失眠和打鼾是常见的睡眠障碍。本研究旨在调查同时存在失眠症状和打鼾与合并症及日间嗜睡的相关性。

方法

研究人群包括来自瑞典 4 个城市的 25901 名参与者(16-75 岁,54.4%为女性),他们通过邮寄问卷回答了有关打鼾、失眠症状(入睡困难和/或维持睡眠困难和/或清晨早醒)、吸烟、教育水平以及呼吸和非呼吸疾病的问题。

结果

4221 人(16.2%)报告打鼾,9872 人(38.1%)报告≥1 项失眠症状。共有 2150 人(8.3%)报告同时存在失眠症状和打鼾。与高血压(调整后的优势比[OR],1.4;95%置信区间[CI],1.2-1.6)、慢性阻塞性肺疾病(调整后的 OR,1.8;95% CI,1.3-2.4)、哮喘(调整后的 OR,1.9;95% CI,1.6-2.3)、日间嗜睡(调整后的 OR,7.9;95% CI,7.1-8.8)和使用催眠药(调整后的 OR,7.5;95% CI,6.1-9.1)的相关性最高。

结论

同时有打鼾和失眠的参与者患高血压、慢性阻塞性肺疾病、哮喘、日间嗜睡和使用催眠药的风险增加。在因失眠寻求医疗帮助的患者中考虑打鼾,以及在因打鼾询问失眠的患者中考虑打鼾都很重要。

参考文献

Hägg SA, Ilieva E, Ljunggren M, et al. The negative health effects of having a combination of snoring and insomnia.. 2022;18(4):973-981.