儿童肥胖与睡眠质量和阻塞性睡眠呼吸暂停与健康相关生活质量的关系。
The association between sleep quality and obstructive sleep apnea with health-related quality of life in children with obesity.
机构信息
Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.
出版信息
J Clin Sleep Med. 2023 Nov 1;19(11):1877-1883. doi: 10.5664/jcsm.10706.
STUDY OBJECTIVES
Obstructive sleep apnea (OSA) and poor sleep quality are highly prevalent in children with obesity, but their individual associations with health-related quality of life (HRQOL) are unknown in this population. The primary objective was to describe the independent association of OSA and sleep quality with HRQOL in children with obesity.
METHODS
This was a cross-sectional study of children with obesity at 2 tertiary care centers. Sleep quality and HRQOL were measured with the Pittsburgh Sleep Quality Index and Pediatric Quality of Life Inventory questionnaires, respectively. Multivariable regression models were created to evaluate associations between OSA and sleep quality with HRQOL.
RESULTS
There were 98 children (median age 15.0 years, median body mass index z-score 3.8, 44% females). Among the study population, 49/98 (50%) children reported poor sleep quality, 41/98 (42%) children had OSA, and 52/98 (53%) children reported impaired HRQOL. Self-reported poor sleep quality was independently associated with reduced HRQOL, whereas the presence of OSA was not. Children with poor sleep quality had a reduced Pediatric Quality of Life Inventory score by 8.8 compared to children with good sleep quality (95% confidence interval, 2.6-14.9; = .006), when adjusting for age, sex, body mass index z-score, attention-deficit/hyperactivity disorder, mood/anxiety disorder, and study site.
CONCLUSIONS
In the current study of children with obesity, we found that HRQOL was more strongly associated with the self-reported experience of sleep than the presence of OSA. Clinicians should assess and optimize sleep quality as part of the evaluation for OSA in children with obesity.
CITATION
Xiao L, Voutsas G, Ryan CM, Katz SL, Narang I. The association between sleep quality and obstructive sleep apnea with health-related quality of life in children with obesity. . 2023;19(11):1877-1883.
研究目的
阻塞性睡眠呼吸暂停（OSA）和睡眠质量差在肥胖儿童中极为常见，但在该人群中，它们与健康相关生活质量（HRQOL）的单独关联尚不清楚。主要目的是描述 OSA 和睡眠质量与肥胖儿童 HRQOL 的独立关联。
方法
这是在 2 家三级保健中心进行的肥胖儿童的横断面研究。睡眠质量和 HRQOL 分别用匹兹堡睡眠质量指数和儿科生活质量量表问卷进行测量。建立多变量回归模型来评估 OSA 和睡眠质量与 HRQOL 之间的关联。
结果
共有 98 名儿童（中位年龄 15.0 岁，中位体重指数 z 评分 3.8，44%为女性）。在研究人群中，49/98（50%）名儿童报告睡眠质量差，41/98（42%）名儿童患有 OSA，52/98（53%）名儿童报告 HRQOL 受损。自我报告的睡眠质量差与 HRQOL 降低独立相关，而 OSA 的存在则不然。与睡眠质量好的儿童相比，睡眠质量差的儿童儿科生活质量量表评分降低了 8.8 分（95%置信区间，2.6-14.9； =.006），调整年龄、性别、体重指数 z 评分、注意缺陷/多动障碍、情绪/焦虑障碍和研究地点后。
结论
在目前肥胖儿童的研究中，我们发现 HRQOL 与自我报告的睡眠体验比 OSA 的存在更密切相关。临床医生应评估和优化睡眠质量，作为肥胖儿童 OSA 评估的一部分。
引文
Xiao L, Voutsas G, Ryan CM, Katz SL, Narang I. 睡眠质量与阻塞性睡眠呼吸暂停与肥胖儿童健康相关生活质量的关系。 2023;19(11):1877-1883.
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