Shanaida Mariia, Hudz Nataliia, Białoń Marietta, Kryvtsowa Maryna, Svydenko Liudmyla, Filipska Anna, Paweł Wieczorek Piotr
Department of Pharmacognosy and Medical Botany, I. Horbachevsky Ternopil National Medical University, Ternopil 4600, Ukraine.
Department of Drug Technology and Biopharmacy, Danylo Halytsky Lviv National Medical University, Lviv 79010, Ukraine.
Saudi J Biol Sci. 2021 Nov;28(11):6145-6152. doi: 10.1016/j.sjbs.2021.06.068. Epub 2021 Jun 26.
The present study was focused on the chemical composition and antimicrobial activity of the essential oils (EsO) obtained from five representatives grown in the south of Ukraine. Among them are L. (cultivar 'Cambridge Scarlet'), (cultivar '2/6-07') (cultivar 'Jalos') and L. The component analysis of the EsO was carried out by gas chromatography method coupled with mass spectrometry (GC-MS). The antimicrobial properties of the EsO were determined using the agar diffusion test against widespread pathogenic bacterial strains () and opportunistic yeast The EsO of and (cultivar 'Jalos') displayed noteworthy antibacterial properties against a wide spectrum of the microorganisms. These antimicrobial properties could be attributed to the high content of aromatic monoterpenoid thymol (52.56% and 47.33%, respectively). The EsO of with the dominance of linalyl acetate (45.51%) and linalool (38.98%) as well as (cultivar '2/6-07') containing citral (27.10%) and -citral (17.11%) demonstrated the strongest antimicrobial effects on typical and clinical strains of with the inhibition zones in the range of 24.0-31.0 mm. The EsO demonstrated the most significant effect against clinical strains of . In conclusion, the present study revealed the chemical composition of five species and cultivars grown in the south of Ukraine and considerable antimicrobial activity of the tested EsO, especially against the typical and clinical strains of and . The obtained results could be perspective for applying in the pharmaceutical industry and for the conservation of food and cosmetic products.
本研究聚焦于从乌克兰南部种植的五个代表性品种中提取的香精油（EsO）的化学成分和抗菌活性。其中包括迷迭香（品种‘剑桥猩红’）、牛至（品种‘2/6 - 07’）、罗勒（品种‘贾洛斯’）和薰衣草。通过气相色谱 - 质谱联用（GC - MS）方法对香精油进行成分分析。使用琼脂扩散试验针对广泛传播的致病细菌菌株（）和机会性酵母测定香精油的抗菌性能。迷迭香和罗勒（品种‘贾洛斯’）的香精油对多种微生物显示出显著的抗菌性能。这些抗菌性能可归因于芳香单萜类百里香酚的高含量（分别为52.56%和47.33%）。以乙酸芳樟酯（45.51%）和芳樟醇（38.98%）为主的薰衣草香精油以及含有柠檬醛（27.10%）和β - 柠檬醛（17.11%）的牛至（品种‘2/6 - 07’）对白色念珠菌的典型菌株和临床菌株表现出最强的抗菌作用，抑菌圈范围在24.0 - 31.0毫米。薰衣草香精油对白色念珠菌的临床菌株显示出最显著的效果。总之，本研究揭示了乌克兰南部种植的五个迷迭香属物种和品种的化学成分以及受试香精油相当可观的抗菌活性，尤其是对白色念珠菌的典型菌株和临床菌株。所得结果在制药行业以及食品和化妆品保存方面具有应用前景。
