Pedrosa-Laza Maria, López-Cheda Ana, Cao Ricardo
Área de Proyectos de Ingeniería, Escuela Técnica Superior de Minas, University of Oviedo, Oviedo, Spain.
Research Group MODES, CITIC, University of A Coruña, 15071 A Coruña, Spain.
Appl Intell (Dordr). 2022;52(1):794-807. doi: 10.1007/s10489-021-02311-8. Epub 2021 May 12.
A short introduction to survival analysis and censored data is included in this paper. A thorough literature review in the field of cure models has been done. An overview on the most important and recent approaches on parametric, semiparametric and nonparametric mixture cure models is also included. The main nonparametric and semiparametric approaches were applied to a real time dataset of COVID-19 patients from the first weeks of the epidemic in Galicia (NW Spain). The aim is to model the elapsed time from diagnosis to hospital admission. The main conclusions, as well as the limitations of both the cure models and the dataset, are presented, illustrating the usefulness of cure models in this kind of studies, where the influence of age and sex on the time to hospital admission is shown.
本文包含生存分析和删失数据的简短介绍。已对治愈模型领域进行了全面的文献综述。还包括对参数、半参数和非参数混合治愈模型最重要和最新方法的概述。主要的非参数和半参数方法应用于来自加利西亚(西班牙西北部)疫情最初几周的新冠肺炎患者实时数据集。目的是对从诊断到入院的时间进行建模。给出了主要结论以及治愈模型和数据集的局限性,说明了治愈模型在这类研究中的有用性,其中展示了年龄和性别对入院时间的影响。