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复合性滤泡性淋巴瘤和经典型霍奇金淋巴瘤。

Composite follicular lymphoma and classic Hodgkin lymphoma.

作者信息

Kim Han-Na, Jeon Min Ji, Yu Eun Sang, Kim Dae Sik, Choi Chul-Won, Ko Young Hyeh

机构信息

Department of Pathology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.

Division of Hematology-Oncology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.

出版信息

J Pathol Transl Med. 2022 Jan;56(1):57-60. doi: 10.4132/jptm.2021.10.09. Epub 2021 Nov 16.

DOI:10.4132/jptm.2021.10.09
PMID:34775730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8743806/
Abstract

Composite lymphoma is very rare and a combination of Hodgkin lymphoma and non-Hodgkin lymphoma and even histiocytic tumors can occur. Because of the unfamiliarity, not only can this cause diagnostic problems, but can also affect treatment plan. We report a case of composite lymphoma in a 40-year-old male. Initial biopsy showed a composite lymphoma of follicular lymphoma grade 1 and classic Hodgkin lymphoma. After chemotherapy, another lymph node was taken because of disease progression, which revealed follicular lymphoma, grade 3a without Hodgkin lymphoma component.

摘要

复合性淋巴瘤非常罕见,霍奇金淋巴瘤与非霍奇金淋巴瘤甚至组织细胞肿瘤都可能合并出现。由于对此并不熟悉,这不仅会引发诊断问题,还会影响治疗方案。我们报告一例40岁男性的复合性淋巴瘤病例。初始活检显示为1级滤泡性淋巴瘤和经典霍奇金淋巴瘤的复合性淋巴瘤。化疗后,因疾病进展又取了一个淋巴结活检,结果显示为3a级滤泡性淋巴瘤,无霍奇金淋巴瘤成分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02da/8743806/f23cae8812b8/jptm-2021-10-09f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02da/8743806/eaf181015b82/jptm-2021-10-09f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02da/8743806/f23cae8812b8/jptm-2021-10-09f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02da/8743806/eaf181015b82/jptm-2021-10-09f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02da/8743806/f23cae8812b8/jptm-2021-10-09f2.jpg

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Am J Surg Pathol. 2022 Jan 1;46(1):58-70. doi: 10.1097/PAS.0000000000001780.
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Int J Hematol. 2021 Apr;113(4):592-599. doi: 10.1007/s12185-020-03035-0. Epub 2021 Jan 2.
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