Kim Han-Na, Jeon Min Ji, Yu Eun Sang, Kim Dae Sik, Choi Chul-Won, Ko Young Hyeh
Department of Pathology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
Division of Hematology-Oncology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
J Pathol Transl Med. 2022 Jan;56(1):57-60. doi: 10.4132/jptm.2021.10.09. Epub 2021 Nov 16.
Composite lymphoma is very rare and a combination of Hodgkin lymphoma and non-Hodgkin lymphoma and even histiocytic tumors can occur. Because of the unfamiliarity, not only can this cause diagnostic problems, but can also affect treatment plan. We report a case of composite lymphoma in a 40-year-old male. Initial biopsy showed a composite lymphoma of follicular lymphoma grade 1 and classic Hodgkin lymphoma. After chemotherapy, another lymph node was taken because of disease progression, which revealed follicular lymphoma, grade 3a without Hodgkin lymphoma component.
复合性淋巴瘤非常罕见,霍奇金淋巴瘤与非霍奇金淋巴瘤甚至组织细胞肿瘤都可能合并出现。由于对此并不熟悉,这不仅会引发诊断问题,还会影响治疗方案。我们报告一例40岁男性的复合性淋巴瘤病例。初始活检显示为1级滤泡性淋巴瘤和经典霍奇金淋巴瘤的复合性淋巴瘤。化疗后,因疾病进展又取了一个淋巴结活检,结果显示为3a级滤泡性淋巴瘤,无霍奇金淋巴瘤成分。