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抗炎饮食的摄入降低了脂肪肝指数。

Anti-inflammatory diet consumption reduced fatty liver indices.

机构信息

Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Social Development and Health Promotion Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Sci Rep. 2021 Nov 19;11(1):22601. doi: 10.1038/s41598-021-98685-3.

Abstract

The aim of this study was to assess the association between dietary inflammatory index (DII) and non-invasive markers of liver status in adults. This cross-sectional study was performed on 8520 adults, recruited in Ravansar Non-Communicable Diseases (RaNCD) cohort study, western Iran. The DII score was calculated based on participants' dietary intakes obtained from Food Frequency Questionnaire (FFQ). Fatty Liver Index (FLI) score was calculated by anthropometric measurements and some non-invasive markers of liver status. Linear regression models were applied to estimate the associations and adjust the possible confounding factors. A greater DII score was significantly associated with higher energy intake, body mass index (BMI), body fat mass (BFM), blood pressure, and FLI (P < 0.001). Participants with the highest DII score had a significantly higher consumption saturated fat, trans fat and red meat than those in the lowest quartile (P < 0.001). After adjustments of age and sex, participants in the highest quartile of the DII score had a greater risk of FLI (β: 0.742, 95% CI: 0.254, 0.601). More pro-inflammatory diet in participants was associated with a higher FLI. The DII score was positively associated with non-invasive liver markers. Thus, having an anti-inflammatory diet can help balance liver enzymes, reduce obesity, and decrease fatty liver.

摘要

本研究旨在评估饮食炎症指数(DII)与成年人非侵入性肝脏状态标志物之间的关系。这项横断面研究在伊朗西部拉万萨尔非传染性疾病(RaNCD)队列研究中对 8520 名成年人进行。DII 评分是根据参与者从食物频率问卷(FFQ)中获得的饮食摄入量计算得出的。脂肪肝指数(FLI)评分通过人体测量和一些非侵入性的肝脏状态标志物计算得出。应用线性回归模型来估计关联并调整可能的混杂因素。较高的 DII 评分与较高的能量摄入、体重指数(BMI)、体脂肪量(BFM)、血压和 FLI 显著相关(P<0.001)。DII 评分最高组的参与者比最低四分位数组的参与者消耗更多的饱和脂肪、反式脂肪和红肉(P<0.001)。在调整年龄和性别后,DII 评分最高组的参与者患 FLI 的风险显著更高(β:0.742,95%CI:0.254,0.601)。参与者中更促炎的饮食与更高的 FLI 相关。DII 评分与非侵入性肝脏标志物呈正相关。因此,抗炎饮食有助于平衡肝酶、减少肥胖和减少脂肪肝。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7af5/8604894/a38b512a6942/41598_2021_98685_Fig1_HTML.jpg

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