使用羟基磷灰石牙膏预防龋齿。
The use of hydroxyapatite toothpaste to prevent dental caries.
机构信息
Faculty of Dentistry, University of Toronto, 124 Edward St., Toronto, M5G 1G6, Canada.
Research Department, Oral Care Dr. Kurt Wolff GmbH & Co. KG, Johanneswerkstr, 34-36, 33611, Bielefeld, Germany.
出版信息
Odontology. 2022 Apr;110(2):223-230. doi: 10.1007/s10266-021-00675-4. Epub 2021 Nov 22.
Abstract
Dissolution of hydroxyapatite from the tooth structure at low pH can lead to the irreversible destruction of enamel and dentin, which if left untreated can result in pain and tooth loss. Hydroxyapatite toothpastes contain hydroxyapatite particles in micro- or nanocrystalline form that have been shown to deposit and restore demineralized enamel surfaces. As such, they are currently being explored as a fluoride-free anti-caries agent. This narrative review article aims to summarize the recent findings of the research investigating the remineralization potential of HAP toothpaste in vitro, in situ and in vivo, as well as some other applications in dentistry.
摘要
在低 pH 值条件下，羟磷灰石从牙齿结构中溶解会导致牙釉质和牙本质的不可逆转破坏，如果不加以治疗，可能会导致疼痛和牙齿丧失。羟磷灰石牙膏含有以微纳米晶体形式存在的羟磷灰石颗粒，已被证明可以在脱矿釉质表面沉积和修复。因此，它们目前正被作为一种无氟防龋剂进行探索。本文综述了近年来关于羟磷灰石牙膏在体外、原位和体内再矿化潜力的研究结果，以及在牙科领域的其他一些应用。
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