Department of Dermatology, University of Connecticut Health Center, Farmington, Connecticut, USA.
Department of Dermatology, University of Connecticut Health Center, Farmington, Connecticut, USA.
Clin Dermatol. 2022 Mar-Apr;40(2):122-127. doi: 10.1016/j.clindermatol.2021.10.004. Epub 2021 Oct 27.
Rosacea is a common chronic inflammatory cutaneous disorder, primarily manifesting on the cheeks, nose, chin, and forehead with a classic relapsing-remitting course that affects mostly fair skin types (Fitzpatrick I and II). The pathogenesis remains unclear, but the complex interplay between environmental and genetic factors may augment the innate immune response and neurovascular dysregulation. Different nutrients may play a role in the pathogenesis of rosacea. Many dietary triggers, including hot beverages, alcohol, spicy foods, caffeine, vanilla, cinnamon, niacin, marinated meats, and dairy products, have been postulated for this disease; however, there is a lack of well-designed and controlled studies evaluating the causal relationship between rosacea and dietary factors. We have explored the available evidence and hypotheses based on trigger-food categories of rosacea, the role of the skin-gut microbiome axis, and potentially benefiting dietary factors such as probiotics, prebiotics, and high-fiber diets.
酒渣鼻是一种常见的慢性炎症性皮肤疾病，主要表现为面中部，特别是面颊、鼻部、眉间和颏部，呈反复发作、缓解的慢性病程，主要影响白皙皮肤人群（Fitzpatrick I 和 II 型）。其发病机制尚不清楚，但环境和遗传因素的复杂相互作用可能增强固有免疫反应和神经血管调节异常。不同的营养物质可能在酒渣鼻的发病机制中起作用。许多饮食诱因，包括热饮、酒精、辛辣食物、咖啡因、香草、肉桂、烟酸、腌制肉类和乳制品，都被推测与这种疾病有关；然而，目前缺乏设计良好和对照研究来评估酒渣鼻与饮食因素之间的因果关系。我们根据酒渣鼻的触发食物类别、皮肤-肠道微生物群轴的作用以及可能有益的饮食因素（如益生菌、益生元和高纤维饮食），探讨了现有证据和假设。
