Heimrich Konstantin G, Prell Tino
Department of Neurology, Jena University Hospital, 07747 Jena, Germany.
Department of Geriatrics, Halle University Hospital, 06120 Halle, Germany.
Brain Sci. 2021 Nov 3;11(11):1460. doi: 10.3390/brainsci11111460.
Parkinson´s disease multimodal complex treatment (PD-MCT) is a multidisciplinary inpatient treatment option increasingly applied in Germany. However, data on its effectiveness are rare. Data were collected at the Department of Neurology of the University Hospital Jena, Germany. In 2019, 159 patients were admitted to our neurology ward for PD-MCT. Patients were followed for up to 12 months, and their data were retrospectively analyzed to assess the short- and long-term treatment effects. The treatment led to an improvement in motor function assessed by Movement Disorder Society sponsored revision of the unified Parkinson´s disease rating scale part III (MDS-UPDRS III) and motor performance (Tinetti test). Improvement of MDS-UPDRS III was associated with lower age, higher MDS-UPDRS III at admission, and less depression (assessed by Hospital Anxiety and Depression Scale and Beck-Depression Inventory II). One month after the hospital stay, 36.8% of the patients reported feeling better, while 32.6% reported feeling worse. If the patients were not depressed, they were more likely to have reported feeling better. PD-MCT is an effective inpatient treatment option. However, to improve patients' satisfaction, screening and treatment for depression is essential. The effectiveness of different treatment durations has to be elucidated in further studies.
帕金森病多模式综合治疗（PD-MCT）是德国越来越多地应用的一种多学科住院治疗方案。然而，关于其有效性的数据很少。数据收集于德国耶拿大学医院神经内科。2019年，159名患者因PD-MCT入住我们的神经科病房。对患者进行了长达12个月的随访，并对他们的数据进行回顾性分析，以评估短期和长期治疗效果。该治疗使通过运动障碍协会赞助修订的统一帕金森病评定量表第三部分（MDS-UPDRS III）评估的运动功能以及运动表现（Tinetti测试）得到改善。MDS-UPDRS III的改善与年龄较小、入院时MDS-UPDRS III较高以及抑郁程度较轻（通过医院焦虑抑郁量表和贝克抑郁量表第二版评估）相关。住院一个月后，36.8%的患者报告感觉好转，而32.6%的患者报告感觉变差。如果患者没有抑郁，他们更有可能报告感觉好转。PD-MCT是一种有效的住院治疗方案。然而，为了提高患者满意度，对抑郁进行筛查和治疗至关重要。不同治疗时长的有效性必须在进一步研究中阐明。
