Central Department of Chemistry, Tribhuvan University, Kathmandu 44618, Nepal.
Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-Ku, Kumamoto 862-0973, Japan.
Biomolecules. 2021 Nov 22;11(11):1738. doi: 10.3390/biom11111738.
(L.) L. (Syn.: (L.) Hassak, Family: Asteraceae) is an important medicinal plant in the tropical and subtropical regions. It is widely used in treating various diseases of skin, liver and stomach in India, Nepal, Bangladesh, and other countries. The main aim of this review was to collect and analyze the available information on traditional uses, phytoconstituents, and biological activities of . The scientific information was collected from the online bibliographic databases such as Scopus, MEDLINE/PubMed, Google Scholar, SciFinder, etc. and books and proceedings. The active phytochemicals were coumestan derivatives, phenolic acid derivatives, flavonoids, triterpenoid and steroid saponins, substituted thiophenes, etc. Various extracts and isolated compounds of showed a wide range of biological activities such as antimicrobial, anticancer, hepatoprotective, neuroprotective and hair growth promoting activities. Relatively a few studies have been performed to reveal the exact phytoconstituents responsible for their corresponding pharmacological activities. Future studies should focus on detailed mechanism based studies using animal models and clinical studies.
(L.) L.（同义词：（L.）Hassak，科：菊科）是热带和亚热带地区一种重要的药用植物。它在印度、尼泊尔、孟加拉国和其他国家被广泛用于治疗各种皮肤、肝脏和胃部疾病。本综述的主要目的是收集和分析有关传统用途、植物化学成分和生物活性的可用信息。科学信息是从 Scopus、MEDLINE/PubMed、Google Scholar、SciFinder 等在线书目数据库以及书籍和会议记录中收集的。活性植物化学成分包括香豆素衍生物、酚酸衍生物、类黄酮、三萜和甾体皂苷、取代噻吩等。[L.] 的各种提取物和分离化合物表现出广泛的生物活性，如抗菌、抗癌、保肝、神经保护和促进毛发生长活性。相对较少的研究已经进行，以揭示负责其相应药理活性的确切植物化学成分。未来的研究应侧重于使用动物模型和临床研究进行详细的基于机制的研究。
