Bustos-Vázquez E, Padilla-González E, Reyes-Gómez D, Carmona-Ramos M C, Monroy-Vargas J A, Benítez-Herrera A E, Meléndez-Mier G
Department of Epidemiology, Secretary of Health of the State of Hidalgo, Pachuca C.P. 42182, Hidalgo, Mexico.
Public Health Subsecretary of the State of Hidalgo, Pachuca C.P. 42182, Hidalgo, Mexico.
Healthcare (Basel). 2021 Oct 22;9(11):1423. doi: 10.3390/healthcare9111423.
The outbreak of SARS-CoV-2 abruptly disseminated in early 2020, overcoming the capacity of health systems to respond the pandemic. It was not until the vaccines were launched worldwide that an increase in survival was observed. The objectives of this study were to analyse the characteristics of survivors and their relationship with comorbidities. We had access to a database containing information on 16,747 hospitalized patients from Mexico, all infected with SARS-CoV-2, as part of a regular follow-up. The descriptive analysis looked for clusters of either success or failure. We categorized the samples into no comorbidities, or one and up to five coexisting with the infection. We performed a logistic regression test to ascertain what factors were more influential in survival. The main variable of interest was survival associated with multimorbidity factors. The database hosted information on hospitalized patients from Mexico between March 2020 through to April 2021. Categories 2 and 3 had the largest number of patients. Survival rates were higher in categories 0 (64.8%), 1 (57.5%) and 2 (51.6%). In total, 1741 (10.5%) patients were allocated to an ICU unit. Mechanical ventilators were used on 1415 patients, corresponding to 8.76%. Survival was recorded in 9575 patients, accounting for 57.2% of the sample population. Patients without comorbidities, younger people and women were more likely to survive.
2020年初,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫情突然蔓延,超出了卫生系统应对这一流行病的能力。直到全球推出疫苗后,生存率才有所提高。本研究的目的是分析幸存者的特征及其与合并症的关系。作为定期随访的一部分,我们可以访问一个数据库,其中包含来自墨西哥的16747名住院患者的信息,这些患者均感染了SARS-CoV-2。描述性分析寻找成功或失败的聚类。我们将样本分为无合并症、或一种合并症以及多达五种与感染并存的合并症。我们进行了逻辑回归测试,以确定哪些因素对生存更有影响。主要关注变量是与多种合并症因素相关的生存情况。该数据库包含了2020年3月至2021年4月期间墨西哥住院患者的信息。第2类和第3类患者数量最多。第0类(64.8%)、第1类(57.5%)和第2类(51.6%)的生存率较高。共有1741名(10.5%)患者被分配到重症监护病房。1415名患者使用了机械通气,占8.76%。9575名患者记录了生存情况,占样本人群的57.2%。无合并症的患者、年轻人和女性更有可能存活。