Mangal Utkarsh, Kim Ji-Yeong, Seo Ji-Young, Kwon Jae-Sung, Choi Sung-Hwan
Department of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of Dentistry, Seoul 03722, Korea.
BK21 PLUS Project, Yonsei University College of Dentistry, Seoul 03722, Korea.
Materials (Basel). 2019 Oct 21;12(20):3438. doi: 10.3390/ma12203438.
Herein we evaluate the effect of nanodiamond (ND) incorporation on the mechanical properties of poly(methyl methacrylate) (PMMA) nanocomposite. Three quantities of ND (0.1, 0.3, and 0.5 wt.%) were tested against the control and zirconium oxide nanoparticles (ZrO). Flexural strength and elastic modulus were measured using a three-point bending test, surface hardness was evaluated using the Vickers hardness test, and surface roughness was evaluated using atomic force microscopy (AFM), while fungal adhesion and viability were studied using . Samples were also analyzed for biofilm thickness and biomass in a saliva-derived biofilm model. All groups of ND-PMMA nanocomposites had significantly greater mean flexural strengths and statistically improved elastic modulus, compared to the control and ZrO groups ( < 0.001). The Vickers hardness values significantly increased compared to the control group ( < 0.001) with 0.3% and 0.5% ND. ND addition also gave significant reduction in fungal adhesion and viability ( < 0.001) compared to the control group. Finally, salivary biofilm formation was markedly reduced compared to the ZrO group. Hence, the incorporation of 0.1-0.5 wt.% ND with auto- polymerized PMMA resin significantly improved the flexural strength, elastic modulus, and surface hardness, and provided considerable fungal resistance.
在此，我们评估了纳米金刚石（ND）掺入对聚甲基丙烯酸甲酯（PMMA）纳米复合材料力学性能的影响。针对对照组和氧化锆纳米颗粒（ZrO）测试了三种含量的ND（0.1、0.3和0.5重量%）。使用三点弯曲试验测量弯曲强度和弹性模量，使用维氏硬度试验评估表面硬度，使用原子力显微镜（AFM）评估表面粗糙度，同时使用[具体方法]研究真菌粘附和活力。还在唾液衍生生物膜模型中分析了样品的生物膜厚度和生物量。与对照组和ZrO组相比，所有组的ND-PMMA纳米复合材料的平均弯曲强度均显著更高，弹性模量在统计学上有所改善（<0.001）。与对照组相比，0.3%和0.5% ND的维氏硬度值显著增加（<0.001）。与对照组相比，添加ND还显著降低了真菌粘附和活力（<0.001）。最后，与ZrO组相比，唾液生物膜形成明显减少。因此，将0.1 - 0.5重量%的ND与自聚合PMMA树脂掺入可显著提高弯曲强度、弹性模量和表面硬度，并提供相当的抗真菌性能。
