Monroy-García Imelda N, Carranza-Torres Irma Edith, Carranza-Rosales Pilar, Oyón-Ardoiz María, García-Estévez Ignacio, Ayala-Zavala Jesús Fernando, Morán-Martínez Javier, Viveros-Valdez Ezequiel
Deparatmento de Química, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Av. Pedro de Alba S/N, San Nicolás de los Garza 66450, Nuevo León, Mexico.
Centro de Investigación Biomédica del Noreste, Instituto Mexicano del Seguro Social, Jesús Dionisio González #501, Col. Independencia, Monterrey 64720, Nuevo León, Mexico.
Foods. 2021 Nov 5;10(11):2710. doi: 10.3390/foods10112710.
Linnaeus (Boraginacea) and Michaux (Sapotaceae) are wild fruits consumed in North America and are appreciated for their pleasant flavor and sweet taste. However, details regarding their composition and biological properties in the available literature are scarce. This study reports the phenolic composition, antioxidant, antiproliferative activities, and digestive enzymatic inhibition of amberlite-retained methanolic extracts from both fruits. Results revealed that these wild fruit extracts are rich in antioxidants. had lower phenolic but higher flavonoid contents (21.4 ± 1.5 mg GAE/100 g FW and 6.42 ± 0.9 mg CE/100 g FW) than (64.7 ± 2.6 mg GAE/100 g FW and 5.1 ± 0.4 mg CE/100 g FW). HPLC-DAD-MS/MS analysis showed rosmarinic acid as a major polyphenol in and quercetin glucoside in . Polyphenols content in was related to a significant free radical scavenging ability: DPPH (EC = 0.32 ± 0.03 mg/mL), TEAC (4134 ± 9.7 μM TE/g dry extract), and hemolysis inhibition (IC = 58.55 ± 2.4 μg/mL). Both extracts were capable of inhibiting -glucosidase, partially inhibiting -amylase, and showed no inhibition against lipase, while showing antiproliferative activity against HeLa, HT-29 and MCF-7 cancer cell lines. Our study revealed that these wild fruit extracts are rich in health-beneficial phytochemicals and hold significant potential for elaborating functional foods.
林奈草（紫草科）和米乔氏李（山榄科）是在北美食用的野生水果，因其宜人的风味和甜味而受到喜爱。然而，现有文献中关于它们的成分和生物学特性的细节很少。本研究报告了这两种水果经琥石树脂保留的甲醇提取物的酚类成分、抗氧化、抗增殖活性和消化酶抑制作用。结果表明，这些野生水果提取物富含抗氧化剂。[此处原文缺失比较对象，无法准确翻译]的酚类含量较低，但黄酮类含量较高（21.4±1.5毫克没食子酸当量/100克鲜重和6.42±0.9毫克儿茶素当量/100克鲜重），而[此处原文缺失比较对象，无法准确翻译]（64.7±2.6毫克没食子酸当量/100克鲜重和5.1±0.4毫克儿茶素当量/100克鲜重）。高效液相色谱-二极管阵列-串联质谱分析表明，迷迭香酸是[此处原文缺失具体水果名称，无法准确翻译]中的主要多酚，而槲皮素葡萄糖苷是[此处原文缺失具体水果名称，无法准确翻译]中的主要多酚。[此处原文缺失具体水果名称，无法准确翻译]中的多酚含量与显著的自由基清除能力相关：二苯基苦味酰基自由基（半数有效浓度=0.32±0.03毫克/毫升）、铁离子还原抗氧化能力（4134±9.7微摩尔 Trolox/克干提取物）和溶血抑制（半数抑制浓度=58.55±2.4微克/毫升）。两种提取物都能够抑制α-葡萄糖苷酶，部分抑制α-淀粉酶，对脂肪酶无抑制作用，同时对宫颈癌HeLa细胞系、结肠腺癌HT-29细胞系和乳腺癌MCF-7细胞系具有抗增殖活性。我们的研究表明，这些野生水果提取物富含对健康有益的植物化学物质，在开发功能性食品方面具有巨大潜力。
