Krajewski Piotr K, Marrón Servando E, Gomez-Barrera Manuel, Tomas-Aragones Lucía, Gilaberte-Calzada Yolanda, Szepietowski Jacek C
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chalubinskiego Street 1, 50-368 Wrocław, Poland.
Aragon Psychodermatology Research Group (GAI + PD), Dermatology Department, University Hospital Miguel Servet, 50009 Zaragoza, Spain.
J Clin Med. 2021 Nov 22;10(22):5446. doi: 10.3390/jcm10225446.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder with well-documented effects on patients' quality of life (QoL). The aim of this study was to evaluate the QoL of patients with HS via the use of a newly developed questionnaire: Hidradenitis Suppurativa Quality of Life-24 (HSQoL-24). This study was performed on a population of 342 HS patients. Their QoL was assessed via the HSQoL-24 questionnaire. The perceived impairment of QoL due to HS in the studied group was considered to be serious (mean HSQoL-24 score: 58.3 ± 21.0 points). Women tended to experience a significantly higher impact from the disease than men (61.6 ± 19.2 points vs. 51.1 ± 23.1 points, < 0.001). The HS severity had an effect on the perceived QoL, with statistically significant differences being evident between the self-assessed HS severity groups. The level of QoL impairment correlated positively with the number of affected body areas ( = 0.285, < 0.001) and the duration of the disease ( = 0.173, = 0.001), while the patients' age at disease onset correlated negatively with the HSQoL-24 global score ( = -0.182, = 0.001). Patients living in their family house scored higher than other groups. The least affected were patients who lived alone. The study shows that the HSQoL-24 questionnaire is a reliable, HS-specific tool for measuring the QoL among patients with HS in real-life clinical settings.
化脓性汗腺炎（HS）是一种慢性炎症性皮肤病，对患者的生活质量（QoL）有明确记载的影响。本研究的目的是通过使用新开发的问卷：化脓性汗腺炎生活质量-24（HSQoL-24）来评估HS患者的生活质量。本研究对342名HS患者进行。通过HSQoL-24问卷评估他们的生活质量。研究组中因HS导致的生活质量感知损害被认为是严重的（HSQoL-24平均得分：58.3±21.0分）。女性往往比男性经历更显著的疾病影响（61.6±19.2分对51.1±23.1分，<0.001）。HS严重程度对生活质量感知有影响，自我评估的HS严重程度组之间存在统计学显著差异。生活质量损害水平与受影响身体部位的数量呈正相关（=0.285，<0.001）和疾病持续时间呈正相关（=0.173，=0.001），而患者发病时的年龄与HSQoL-24总体得分呈负相关（=-0.182，=0.001）。居住在自家房子里的患者得分高于其他组。受影响最小的是独居患者。该研究表明，HSQoL-24问卷是一种可靠的、针对HS的工具，用于在现实临床环境中测量HS患者的生活质量。
