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经颅直流电刺激联合视觉提示训练对帕金森病患者运动功能、平衡和步态能力的影响

The Effect of Transcranial Direct Current Stimulation Combined with Visual Cueing Training on Motor Function, Balance, and Gait Ability of Patients with Parkinson's Disease.

作者信息

Lee Si-A, Kim Myoung-Kwon

机构信息

Department of Rehabilitation Sciences, Graduate School, Daegu University, Jillyang, Gyeongsan, Gyeongbuk 712-714, Korea.

Department of Physical Therapy, College of Rehabilitation Sciences, Daegu University, Jillyang, Gyeongsan, Gyeongbuk 712-714, Korea.

出版信息

Medicina (Kaunas). 2021 Oct 22;57(11):1146. doi: 10.3390/medicina57111146.

DOI:10.3390/medicina57111146
PMID:34833364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8617912/
Abstract

: The purpose of this study was to investigate the effects of transcranial direct current stimulation (tDCS) on motor function, balance and gait ability in patients with Parkinson's disease (PD). : For the experiment, 30 patients with PD were randomly assigned to the experimental group ( = 15) and the control group ( = 15). Visual cueing training was commonly applied to both groups, the experimental group applied tDCS simultaneously with visual training, and the control group applied sham tDCS simultaneously with visual training. All subjects were pre-tested before the first intervention, post-tested after completing all 4 weeks of intervention, and followed-up tested 2 weeks after the completing intervention. The tests used the Unified Parkinson's Disease Rating Scale (UPDRS) for motor function assessment, Functional Gait Assessment (FGA) for balance assessment, Freezing of Gait Questionnaire (FOG-Q) and the GAITRite system for gait ability assessment. Among the data obtained through the GAITRite system, gait velocity, cadence, step time, double support time, and stride length were analyzed. : The experimental group showed a significant decrease in UPDRS and a significant increase in FGA and cadence after the intervention. In addition, UPDRS and cadence showed a significant difference in the follow-up test compared to the pre-intervention test. : This study suggests that the application of tDCS to the supplementary motor area of PD patients is useful as an adjuvant therapy for rehabilitation training of PD patients.

摘要

本研究旨在探讨经颅直流电刺激(tDCS)对帕金森病(PD)患者运动功能、平衡和步态能力的影响。在该实验中,30例PD患者被随机分为实验组(n = 15)和对照组(n = 15)。两组均进行视觉提示训练,实验组在视觉训练的同时应用tDCS,对照组在视觉训练的同时应用伪tDCS。所有受试者在首次干预前进行预测试,在完成所有4周干预后进行后测试,并在完成干预2周后进行随访测试。测试使用统一帕金森病评定量表(UPDRS)进行运动功能评估,使用功能性步态评估(FGA)进行平衡评估,使用步态冻结问卷(FOG-Q)和GAITRite系统进行步态能力评估。在通过GAITRite系统获得的数据中,分析了步态速度、步频、步幅时间、双支撑时间和步幅长度。干预后,实验组的UPDRS显著降低,FGA和步频显著增加。此外,与干预前测试相比,随访测试中的UPDRS和步频显示出显著差异。本研究表明,将tDCS应用于PD患者的辅助运动区作为PD患者康复训练的辅助治疗是有用的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/d41fbc875f9d/medicina-57-01146-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/f1a00ee3d6a1/medicina-57-01146-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/bf1edcdd9d6f/medicina-57-01146-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/5a8afa47d902/medicina-57-01146-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/d41fbc875f9d/medicina-57-01146-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/f1a00ee3d6a1/medicina-57-01146-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/bf1edcdd9d6f/medicina-57-01146-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/5a8afa47d902/medicina-57-01146-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/2914c8fcd5c9/medicina-57-01146-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8617912/d41fbc875f9d/medicina-57-01146-g001.jpg

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