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饮食习惯与应用普伐他汀治疗血脂异常患者的血脂控制情况的关系。

Relationship between Dietary Habits and Control of Lipid Profiles in Patients with Dyslipidemia Using Pravastatin.

机构信息

International Healthcare Center, Asan Medical Center, Seoul 05505, Korea.

Department of Family Medicine, Central Veterans Hospital, Seoul 05368, Korea.

出版信息

Nutrients. 2021 Oct 25;13(11):3784. doi: 10.3390/nu13113784.

DOI:10.3390/nu13113784
PMID:34836040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8620026/
Abstract

We investigated the association between dietary habits, evaluated using the modified Mini Dietary Assessment Index for Koreans (MDA), and lipid control among patients aged ≥20 years who had used pravastatin for dyslipidemia for 6 months. Participants were administered questionnaires regarding sociodemographic characteristics and lifestyle factors. Odds ratios and 95% confidence intervals for the control of low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), and total cholesterol (TC) at 6 months for each category of the modified MDA items were calculated through multivariate logistic regression analysis. The odds for controlled LDL-C was higher among those who consumed cholesterol-rich foods <1 time/week (3.27, 1.25-8.57) than for those who did so ≥4 times/week. The odds for controlled TG was higher among those who always consumed dairy products (2.96, 1.36-6.44), ate protein-rich foods three times/day (2.94, 1.06-8.10), and had a regular eating schedule (3.02, 1.30-7.00) than among those who did not have any of these. The odds for controlled TC was higher among those with a regular eating schedule (3.47, 1.55-7.76) than among their counterparts. Patients with dyslipidemia should consume less cholesterols, consume more dairy and protein-rich foods, and follow a regular eating schedule to control lipid profiles.

摘要

我们调查了饮食习惯(采用改良后的韩国迷你饮食评估指数(MDA)进行评估)与使用普伐他汀治疗血脂异常 6 个月的≥20 岁患者血脂控制之间的关联。参与者接受了关于社会人口统计学特征和生活方式因素的问卷调查。通过多变量逻辑回归分析,计算了改良 MDA 项目各分类的 LDL-C、TG 和 TC 控制的 6 个月时的比值比和 95%置信区间。与每周食用胆固醇丰富的食物≥4 次的人相比,每周食用胆固醇丰富的食物<1 次的人 LDL-C 控制的几率更高(3.27,1.25-8.57)。与从不食用这些食物的人相比,始终食用乳制品(2.96,1.36-6.44)、每天食用 3 次富含蛋白质的食物(2.94,1.06-8.10)和有规律的进食时间(3.02,1.30-7.00)的人 TG 控制的几率更高。与没有规律进食时间的人相比,有规律进食时间的人 TC 控制的几率更高(3.47,1.55-7.76)。血脂异常患者应减少胆固醇摄入,增加乳制品和富含蛋白质的食物摄入,并遵循规律的进食时间来控制血脂谱。

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