Sargent College of Health and Rehabilitation Sciences.
Department of Psychological and Brain Sciences.
Psychol Assess. 2022 Mar;34(3):205-216. doi: 10.1037/pas0001080. Epub 2021 Nov 29.
Psychosocial functioning impairment is prevalent in first-episode psychosis and chronic schizophrenia. The Quality of Life Scale (QLS) is a widely used tool to measure psychosocial functioning; however, given the overlap between negative symptoms and functioning, along with the QLS being conceptualized initially as a measure of the deficit syndrome, it is unclear whether summing QLS items into a total score is an appropriate measure of overall psychosocial functioning. This study aimed to examine the centrality of QLS items and the appropriateness of using a QLS total score. Participants with first-episode psychosis ( = 404) completed the QLS. Item centrality was assessed using a network analysis approach, while reliability and dimensionality of the QLS total score and subscales were measured using bifactor modeling and related psychometric indices. Network analysis results showed that an item relating to motivation was the most central item within the scale. Moreover, bifactor modeling results found that motivation and other items relating to negative symptoms may reflect the QLS total score more strongly than other functioning (i.e., Interpersonal, Instrumental) domains. Based on these findings, we urge researchers to use caution when using a QLS total score, as it may unequally confound functional domains and motivation. Moreover, our results continue to underscore the importance of negative symptoms, particularly motivational impairment, in psychosocial functioning. Future studies should aim to examine the centrality of other functioning measures in psychosis and schizophrenia, as our results suggest that psychosocial functioning may be greatly influenced by motivation. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
心理社会功能障碍在首发精神病和慢性精神分裂症中较为普遍。生活质量量表(QLS)是一种广泛用于测量心理社会功能的工具;然而,鉴于负性症状和功能之间存在重叠,以及 QLS 最初被概念化为缺陷综合征的测量工具,因此,将 QLS 项目汇总为总分是否是心理社会功能的总体测量方法尚不清楚。本研究旨在检验 QLS 项目的中心性以及使用 QLS 总分的适当性。首发精神病患者(n=404)完成了 QLS。使用网络分析方法评估项目中心性,同时使用双因素模型和相关心理测量指标测量 QLS 总分和分量表的可靠性和维度。网络分析结果表明,与动机相关的项目是该量表中最中心的项目。此外,双因素模型结果发现,动机和其他与负性症状相关的项目可能比其他功能(即人际关系、工具性)领域更强烈地反映 QLS 总分。基于这些发现,我们敦促研究人员在使用 QLS 总分时要谨慎,因为它可能会以不平等的方式混淆功能领域和动机。此外,我们的研究结果继续强调了负性症状的重要性,特别是动机障碍,在心理社会功能中的重要性。未来的研究应该旨在检验其他精神病和精神分裂症中功能测量的中心性,因为我们的结果表明,心理社会功能可能会受到动机的极大影响。