School of Mathematics and Statistics, Changchun University of Technology, Changchun, China.
Department of Statistics, The Chinese University of Hong Kong, Hong Kong, China.
Stat Med. 2022 Mar 30;41(7):1263-1279. doi: 10.1002/sim.9271. Epub 2021 Nov 30.
In many scientific fields, partly interval-censored data, which consist of exactly observed and interval-censored observations on the failure time of interest, appear frequently. However, methodological developments in the analysis of partly interval-censored data are relatively limited and have mainly focused on additive or proportional hazards models. The general linear transformation model provides a highly flexible modeling framework that includes several familiar survival models as special cases. Despite such nice features, the inference procedure for this class of models has not been developed for partly interval-censored data. We propose a fully Bayesian approach coped with efficient Markov chain Monte Carlo methods to fill this gap. A four-stage data augmentation procedure is introduced to tackle the challenges presented by the complex model and data structure. The proposed method is easy to implement and computationally attractive. The empirical performance of the proposed method is evaluated through two simulation studies, and the model is then applied to a dental health study.
在许多科学领域中,部分区间删失数据经常出现,这些数据包括对感兴趣的失效时间的精确观测和区间删失观测。然而,部分区间删失数据的分析方法的发展相对有限,主要集中在加性或比例风险模型上。广义线性变换模型提供了一个高度灵活的建模框架,包括几个常见的生存模型作为特例。尽管具有如此出色的特点,但对于这类模型,尚未为部分区间删失数据开发出推理程序。我们提出了一种完全贝叶斯方法,通过有效的马尔可夫链蒙特卡罗方法来填补这一空白。引入了一个四阶段的数据增强过程来解决复杂模型和数据结构带来的挑战。所提出的方法易于实现,并且具有计算吸引力。通过两项模拟研究评估了所提出方法的经验性能,然后将该模型应用于一项牙齿健康研究。