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使用集成分类器检测癫痫发作中的发作前期状态。

Detection of preictal state in epileptic seizures using ensemble classifier.

作者信息

Usman Syed Muhammad, Khalid Shehzad, Jabbar Sohail, Bashir Sadaf

机构信息

Department of Computer Engineering, Bahria University, Islamabad, Pakistan.

Department of Computational Sciences, The University of Faisalabad, Pakistan.

出版信息

Epilepsy Res. 2021 Dec;178:106818. doi: 10.1016/j.eplepsyres.2021.106818. Epub 2021 Nov 25.

Abstract

OBJECTIVE

Epilepsy affected patient experiences more than one frequency seizures which can not be treated with medication or surgical procedures in 30% of the cases. Therefore, an early prediction of these seizures is inevitable for these cases to control them with therapeutic interventions.

METHODS

In recent years, researchers have proposed multiple deep learning based methods for detection of preictal state in electroencephalogram (EEG) signals, however, accurate detection of start of preictal state remains a challenge. We propose a novel ensemble classifier based method that gets the comprehensive feature set as input and combines three different classifiers to detect the preictal state.

RESULTS

We have applied the proposed method on the publicly available scalp EEG dataset CHBMIT of 22 subjects. An average accuracy of 94.31% with sensitivity and specificity of 94.73% and 93.72% respectively has been achieved with the method proposed in this study.

CONCLUSIONS

Proposed study utilizes the preprocessing techniques for noise removal, combines deep learning based and handcrafted features and an ensemble classifier for detection of start of preictal state. Proposed method gives better results in terms of accuracy, sensitivity, and specificity.

摘要

目的

癫痫患者会经历不止一种发作频率,在30%的病例中,药物或手术治疗无法对其进行治疗。因此,对于这些病例,早期预测这些发作对于通过治疗干预来控制发作是必不可少的。

方法

近年来,研究人员提出了多种基于深度学习的方法来检测脑电图(EEG)信号中的发作前期状态,然而,准确检测发作前期状态的起始仍然是一个挑战。我们提出了一种基于新颖集成分类器的方法,该方法将综合特征集作为输入,并结合三种不同的分类器来检测发作前期状态。

结果

我们将所提出的方法应用于22名受试者的公开可用头皮脑电图数据集CHBMIT。本研究提出的方法实现了平均准确率94.31%,灵敏度和特异度分别为94.73%和93.72%。

结论

所提出的研究利用预处理技术去除噪声,结合基于深度学习的特征和手工特征以及一个集成分类器来检测发作前期状态的起始。所提出的方法在准确率、灵敏度和特异度方面给出了更好的结果。

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