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比利时非工作时间初级医疗中局部眼用皮质类固醇和抗生素的过度处方

Overprescribing of Topical Ocular Corticosteroids and Antibiotics in Out-of-Hours Primary Care in Belgium.

作者信息

De Loof Hans, De Win Ellen, Moens Nathalie, Verhoeven Veronique, Van Royen Paul, Kreps Elke O, Philips Hilde

机构信息

Laboratory of Physiopharmacology, Department of Pharmaceutical Sciences, University of Antwerp, Antwerp, Belgium.

Research Group, Primary and Interdisciplinary Care (ELIZA), Department Family Medicine and Population Health (FAMPOP) University of Antwerp, Antwerp, Belgium.

出版信息

Drug Healthc Patient Saf. 2021 Nov 23;13:229-232. doi: 10.2147/DHPS.S339141. eCollection 2021.

Abstract

Prescribing patterns by primary care physicians concerning ophthalmic problems were studied using the iCAREdata, a database containing information from the out-of-hours care setting in the Flanders region of Belgium. A very high percentage of prescribed ophthalmic medication was topical antibiotics (89.4%) with tobramycin as the most prevalent substance and in clear conflict with the prevailing guidelines. In addition, a very substantial fraction of prescribed medication contained corticosteroids (30.4%). This is a potentially unsafe option within the technical infrastructure of this setting, which limits the diagnostic possibilities concerning viral infections or preexisting glaucoma risk. We conclude that more efforts are required to limit unnecessary and inappropriate prescribing behavior to further promote patient safety.

摘要

使用iCAREdata研究了初级保健医生针对眼科问题的处方模式,该数据库包含比利时弗拉芒地区非工作时间护理机构的信息。所开处方的眼科药物中,局部用抗生素的比例非常高(89.4%),其中妥布霉素是最常用的药物,这与现行指南明显冲突。此外,所开处方药物中有很大一部分含有皮质类固醇(30.4%)。在这种环境的技术条件下,这是一个潜在不安全的选择,因为它限制了对病毒感染或既往青光眼风险的诊断可能性。我们得出结论,需要做出更多努力来限制不必要和不适当的处方行为,以进一步提高患者安全性。

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Steroid-induced glaucoma: Epidemiology, pathophysiology, and clinical management.类固醇性青光眼:流行病学、病理生理学和临床管理。
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