Type IX collagen is a potent inducer of PGE2 and interleukin 1 production by human monocyte macrophages.
作者信息
Dayer J M, Ricard-Blum S, Kaufmann M T, Herbage D
出版信息
FEBS Lett. 1986 Mar 31;198(2):208-12. doi: 10.1016/0014-5793(86)80406-9.
PMID:3485541
Abstract
Type IX collagen and its collagenous fragments are potent stimulatory agents on human blood mononuclear cells for the production of prostaglandin E2 and interleukin 1/mononuclear cell factor. Type IX collagen is 2-4-fold more potent that type I and II and 1 alpha-, 2 alpha- and 3 alpha-collagens. This property may be important in the destructive process of cartilage in inflammatory diseases.
摘要
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