Department of Biology, Duke University, Durham, NC, USA.
Wageningen University, Laboratory of Biochemistry, Wageningen, the Netherlands.
Curr Opin Plant Biol. 2022 Feb;65:102136. doi: 10.1016/j.pbi.2021.102136. Epub 2021 Nov 29.
Transcriptional regulation underlies many of the growth and developmental processes that shape plants as well as their adaptation to their environment. Key to transcriptional control are transcription factors, DNA-binding proteins that serve two essential functions: to find the appropriate DNA contact sites in their target genes; and to recruit other proteins to execute transcriptional transactions. In recent years, protein structural, genomic, bioinformatic, and proteomic analyses have led to new insights into how these central functions are regulated. Here, we review new findings relating to plant transcription factor function and to their role in shaping transcription in the context of chromatin.
转录调控是植物生长发育以及适应环境的重要过程之一。转录因子是 DNA 结合蛋白，是转录调控的关键，它们具有两个重要功能：找到靶基因中合适的 DNA 结合位点；招募其他蛋白执行转录过程。近年来，蛋白质结构、基因组、生物信息学和蛋白质组学分析使我们对这些核心功能的调控机制有了新的认识。本文综述了与植物转录因子功能及其在染色质背景下塑造转录的相关新发现。
