采用低成本、无光纤嵌入式二极管激光器的快速扩散相关光谱技术。
Fast diffuse correlation spectroscopy with a low-cost, fiber-less embedded diode laser.
作者信息
Biswas Arindam, Moka Sadhu, Muller Andreas, Parthasarathy Ashwin B
机构信息
Department of Electrical Engineering, University of South Florida, 4202 E. Fowler Avenue, ENG030, Tampa, FL 33620, USA.
Department of Physics, University of South Florida, 4202 E. Fowler Avenue, ISA2019, Tampa, FL 33620, USA.
出版信息
Biomed Opt Express. 2021 Oct 4;12(11):6686-6700. doi: 10.1364/BOE.435136. eCollection 2021 Nov 1.
Abstract
Diffuse correlation spectroscopy (DCS), a popular optical technique for fast noninvasive measurement of blood flow, is commonly implemented using expensive fiber-coupled long coherence length laser systems. Here, we report the development of a portable and fiber-less approach that can be used as a low-cost alternative to illuminate tissue in DCS instruments. We validate the accuracy and noise characteristics of the fiber-less DCS laser source, by comparisons against traditional DCS light sources, with experiments on controlled tissue-simulating phantoms and in humans.
摘要
扩散相关光谱学（DCS）是一种用于快速无创测量血流的常用光学技术，通常使用昂贵的光纤耦合长相干长度激光系统来实现。在此，我们报告了一种便携式无光纤方法的开发，该方法可作为一种低成本替代方案，用于在DCS仪器中照射组织。我们通过与传统DCS光源进行比较，在受控的组织模拟体模和人体上进行实验，验证了无光纤DCS激光源的准确性和噪声特性。
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