Zhou Wenjun, Zhao Mingjun, Srinivasan Vivek J
China Jiliang University, College of Optical and Electronic Technology, Hangzhou, China.
University of California Davis, Department of Biomedical Engineering, Davis, California, United States.
Neurophotonics. 2023 Jan;10(1):013502. doi: 10.1117/1.NPh.10.1.013502. Epub 2022 Oct 22.
The field of diffuse optics has provided a rich set of neurophotonic tools to measure the human brain noninvasively. Interferometric detection is a recent, exciting methodological development in this field. The approach is especially promising for the measurement of diffuse fluctuation signals related to blood flow. Benefitting from inexpensive sensor arrays, the interferometric approach has already dramatically improved throughput, enabling the measurement of brain blood flow faster and deeper. The interferometric approach can also achieve time-of-flight resolution, improving the accuracy of acquired signals. We provide a historical perspective and summary of recent work in the nascent area of interferometric diffuse optics. We predict that the convergence of interferometric technology with existing economies of scale will propel many advances in the years to come.
漫射光学领域提供了一系列丰富的神经光子学工具，用于非侵入性地测量人类大脑。干涉测量检测是该领域最近一项令人兴奋的方法学进展。这种方法在测量与血流相关的漫射波动信号方面特别有前景。得益于廉价的传感器阵列，干涉测量方法已经显著提高了通量，能够更快、更深入地测量脑血流量。干涉测量方法还可以实现飞行时间分辨率，提高采集信号的准确性。我们提供了干涉漫射光学这一新兴领域的历史视角和近期工作综述。我们预测，干涉测量技术与现有规模经济的融合将在未来几年推动诸多进展。
