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疾病致死性影响因素的数学指标。

Mathematical indices for the influence of risk factors on the lethality of a disease.

机构信息

Departmento de Teoría e Historia Económica, Universidad de Granada, Granada, Spain.

I.U. Centro de Investigación Operativa (CIO), Universidad Miguel Hernández de Elche, Elche, Spain.

出版信息

J Math Biol. 2021 Dec 8;83(6-7):74. doi: 10.1007/s00285-021-01700-4.

DOI:10.1007/s00285-021-01700-4
PMID:34878616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8653415/
Abstract

We develop a theoretical model to measure the relative relevance of different pathologies of the lethality of a disease in society. This approach allows a ranking of diseases to be determined, which can assist in establishing priorities for vaccination campaigns or prevention strategies. Among all possible measurements, we identify three families of rules that satisfy a combination of relevant properties: neutrality, irrelevance, and one of three composition concepts. One of these families includes, for instance, the Shapley value of the associated cooperative game. The other two families also include simple and intuitive indices. As an illustration, we measure the relative relevance of several pathologies in lethality due to COVID-19.

摘要

我们开发了一个理论模型来衡量疾病在社会中的不同病理对死亡率的相对相关性。这种方法可以对疾病进行排序,从而有助于确定疫苗接种运动或预防策略的优先次序。在所有可能的测量方法中,我们确定了满足中性、不相关性和三个组合概念之一的三个规则族:其中一个规则族包括相关合作博弈的 Shapley 值。另外两个规则族还包括简单直观的指标。例如,我们衡量了 COVID-19 致死率中几种病理的相对相关性。

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The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) - China, 2020.2019新型冠状病毒病(COVID-19)疫情的流行病学特征 - 中国,2020年
China CDC Wkly. 2020 Feb 21;2(8):113-122.
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Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study.死于 SARS-CoV-2:罗马尼亚 COVID-19 多中心合并症研究。
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Comorbidity and its Impact on Patients with COVID-19.合并症及其对COVID-19患者的影响。
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The Role of Health Preconditions on COVID-19 Deaths in Portugal: Evidence from Surveillance Data of the First 20293 Infection Cases.健康前提条件对葡萄牙新冠肺炎死亡病例的影响:来自前20293例感染病例监测数据的证据
J Clin Med. 2020 Jul 24;9(8):2368. doi: 10.3390/jcm9082368.
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Predicting Mortality Due to SARS-CoV-2: A Mechanistic Score Relating Obesity and Diabetes to COVID-19 Outcomes in Mexico.预测因 SARS-CoV-2 导致的死亡率:一个将肥胖和糖尿病与墨西哥 COVID-19 结局相关联的机制评分。
J Clin Endocrinol Metab. 2020 Aug 1;105(8). doi: 10.1210/clinem/dgaa346.
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Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area.在纽约市地区,5700 名因 COVID-19 住院的患者的特征、合并症和结局。
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Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis.中国 COVID-19 患者 1590 例的合并症及其影响:一项全国性分析。
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.中国武汉成人 COVID-19 住院患者的临床病程和死亡危险因素:一项回顾性队列研究。
Lancet. 2020 Mar 28;395(10229):1054-1062. doi: 10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.
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