Cardiovascular Medicine Center Zurich, Hirslanden Klinik im Park, Seestrasse 247, Zurich, Switzerland; Institute of Sports Medicine and Science, Rome, Italy.
Cardiovascular Medicine Center Zurich, Hirslanden Klinik im Park, Seestrasse 247, Zurich, Switzerland.
Int J Cardiol. 2022 Feb 1;348:157-162. doi: 10.1016/j.ijcard.2021.12.009. Epub 2021 Dec 9.
A variability in cardiac remodeling is observed in athletes regardless of age, sex, body size and sport participated. We sought to investigate whether other individual characteristics could affect the extent of Left ventricular hypertrophy (LVH).
From 2120 consecutive Olympic athletes, those with LVH (defined as LV Wall thickness ≥ 13 mm) were matched 1:1 by age, gender, body surface area and type of sport with non-LVH Athletes. Clinical and Echocardiographic variables were compared.
48 athletes with LVH (2.3%) and 48 matched non-LVH athletes were identified. LVH Athletes had higher body weight (90 ± 18 vs 81 ± 11Kg; p = 0.006) body mass index (26 ± 2 vs 24 ± 2 Kg/m2; p < 0.001) and body fat percentage (15 ± 7% vs 12 ± 4%; p = 0.016) compared to non-LVH Athletes. They also had higher systolic (123 ± 1 vs 116 ± 11 mmHg; p = 0.002) and diastolic blood pressure (76 ± 8 vs 71 ± 9 mmHg; p = 0.002). On exercise testing, LVH Athletes reached a lower index workload (3.7 ± 0.9 vs 4.1 ± 0.8 W/Kg; p = 0.013) and a higher peak diastolic blood pressure (79 ± 10 vs 74 ± 11 mmHg; p = 0.012) than those without LVH. Binary logistic regression analysis showed that diastolic blood pressure (OR 1.052; 95% CI from 1.011 to 1.130; p = 0.020) and BMI (OR 1.220; 95% CI from 1.016 to 1.465; p = 0.033) had the strongest association with LVH as categorical variable.
Our study showed that increased blood pressure at rest and during exercise, together with larger body weight, body mass and fat percentage are associated with a higher degree of LVH, which is not associated with a greater physical performance and therefore possibly disproportionate to the sport activity.
无论年龄、性别、体型和参与的运动如何，运动员的心脏重构都存在差异。我们试图研究其他个体特征是否会影响左心室肥厚（LVH）的程度。
从 2120 名连续的奥林匹克运动员中，选择 LVH（定义为 LV 壁厚度≥13mm）的运动员与非 LVH 运动员按年龄、性别、体表面积和运动类型 1:1 匹配。比较临床和超声心动图变量。
确定了 48 名 LVH（2.3%）运动员和 48 名匹配的非 LVH 运动员。LVH 运动员的体重（90±18 与 81±11kg；p=0.006）、体重指数（26±2 与 24±2kg/m2；p<0.001）和体脂百分比（15±7%与 12±4%；p=0.016）高于非 LVH 运动员。与非 LVH 运动员相比，他们的收缩压（123±1 与 116±11mmHg；p=0.002）和舒张压（76±8 与 71±9mmHg；p=0.002）也更高。在运动试验中，LVH 运动员达到的指数工作量较低（3.7±0.9 与 4.1±0.8W/Kg；p=0.013），峰值舒张压较高（79±10 与 74±11mmHg；p=0.012）。二元逻辑回归分析显示，舒张压（OR 1.052；95%CI 从 1.011 到 1.130；p=0.020）和 BMI（OR 1.220；95%CI 从 1.016 到 1.465；p=0.033）与 LVH 作为分类变量的关联性最强。
我们的研究表明，静息和运动时血压升高，以及更大的体重、体重指数和体脂百分比与 LVH 程度较高有关，与更高的身体表现无关，因此可能与运动活动不成比例。
