Department of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA.
Department of Chemistry and the Beckman Institute, University of Illinois Urbana Champaign, IL 61801, USA.
Lab Chip. 2021 Dec 21;22(1):40-46. doi: 10.1039/d1lc00758k.
We report a silicon microfluidic platform that enables monolithic integration of transparent micron-scale microfluidic channels, an on-chip segmentation of analyte flows into picoliter-volume droplets, and a nano-electrospray ionization emitter that enables spatial and temporal separation of oil and aqueous phases during electro-spray for subsequent mass spectrometry analysis.
我们报告了一种硅基微流控平台,该平台能够实现透明微尺度微流道的单片集成、将分析物流在片内分割成皮升级别的液滴、以及纳电喷雾电离发射器,从而在电喷雾过程中实现油相和水相的空间和时间分离,以便随后进行质谱分析。