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0.4%三果汤与0.12%氯己定漱口水对14 - 15岁学龄儿童牙菌斑、牙龈炎症及微生物生长的影响:一项随机对照临床试验

Effect of 0.4% Triphala and 0.12% chlorhexidine mouthwash on dental plaque, gingival inflammation, and microbial growth in 14-15-year-old schoolchildren: A randomized controlled clinical trial.

作者信息

Bhor Ketaki, Shetty Vittaldas, Garcha Vikram, Ambildhok Kadambari, Vinay Vineet, Nimbulkar Gargi

机构信息

Department of Public Health Dentistry, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.

Department of Public Health Dentistry, Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, India.

出版信息

J Indian Soc Periodontol. 2021 Nov-Dec;25(6):518-524. doi: 10.4103/jisp.jisp_338_20. Epub 2021 Nov 1.

Abstract

CONTEXT

A strong correlation exists between plaque and dental caries and periodontal diseases. Ayurvedic drugs have been used since ancient times; oral rinses made from these are used in periodontal therapy. Triphala is one of these with wide spectrum of activity.

AIMS

To assess and compare the effect of 0.4% Triphala and 0.12% chlorhexidine (CHX) mouthwash on dental plaque, gingival inflammation, and microbial count of , , and Lactobacilli from dental plaque sample of 14-15-year-old schoolchildren of Pune city during 90 days supervised use.

SETTINGS AND DESIGN

A randomized, controlled, double-blind, parallel-group clinical trial was conducted among 72 schoolchildren aged 14-15 years.

SUBJECTS AND METHODS

Children were divided into two study groups: Group A with 0.4% Triphala mouthwash ( = 36) and Group B with 0.12% CHX mouthwash ( = 36). The plaque Index (Loe H [1967]), gingival index (Loe H and Silness J [1963]), and microbial analysis were recorded at baseline, 30 days, and 90 days interval.

STATISTICAL ANALYSIS USED

Statistical analysis was done using unpaired -test for group-wise comparison and one-way analysis of variance test, followed by Tukey's test for intragroup comparison. < 0.05 was considered statistically significant.

RESULTS

The results showed that 0.4% Triphala and 0.12% CHX have similar inhibitory effect on plaque accumulation, gingivitis, and growth of , , and Lactobacilli.

CONCLUSION

Herbal mouthwash proved to be helpful in reducing plaque microbial counts, plaque, and gingival inflammation and opens new arenas in the field of herbal dentistry and chemical plaque control.

摘要

背景

牙菌斑与龋齿和牙周疾病之间存在密切关联。阿育吠陀药物自古以来就被使用;由这些药物制成的口腔含漱液用于牙周治疗。三果木就是其中一种具有广泛活性的药物。

目的

评估并比较0.4%三果木漱口水和0.12%氯己定(CHX)漱口水对浦那市14 - 15岁学童牙菌斑样本在90天监督使用期间的牙菌斑、牙龈炎症以及变形链球菌、远缘链球菌和乳酸杆菌微生物计数的影响。

设置与设计

对72名14 - 15岁的学童进行了一项随机、对照、双盲、平行组临床试验。

对象与方法

儿童被分为两个研究组:A组使用0.4%三果木漱口水(n = 36),B组使用0.12% CHX漱口水(n = 36)。在基线、30天和90天间隔时记录菌斑指数(Loe H [1967])、牙龈指数(Loe H和Silness J [1963])以及微生物分析结果。

所用统计分析方法

采用不成对t检验进行组间比较,单向方差分析检验,随后采用Tukey检验进行组内比较。P < 0.05被认为具有统计学意义。

结果

结果表明,0.4%三果木漱口水和0.12% CHX漱口水对菌斑积聚、牙龈炎以及变形链球菌、远缘链球菌和乳酸杆菌的生长具有相似的抑制作用。

结论

草药漱口水被证明有助于减少菌斑微生物计数、牙菌斑和牙龈炎症,并在草药牙科和化学菌斑控制领域开辟了新的领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7598/8603804/23f4f6c2059a/JISP-25-518-g001.jpg

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