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新冠大流行期间的睡眠和日间问题,以及冠状病毒感染、隔离和经济困难的影响:使用协调问卷的跨国调查。

Sleep and daytime problems during the COVID-19 pandemic and effects of coronavirus infection, confinement and financial suffering: a multinational survey using a harmonised questionnaire.

机构信息

Department of Clinical Neurosciences, University of Helsinki Clinicum Unit, Helsinki, Finland

Helsinki Sleep Clinic, Terveystalo Healthcare Services, Helsinki, Finland.

出版信息

BMJ Open. 2021 Dec 13;11(12):e050672. doi: 10.1136/bmjopen-2021-050672.

Abstract

OBJECTIVES

Sleep is important for human health and well-being. No previous study has assessed whether the COVID-19 pandemic impacts sleep and daytime function across the globe.

METHODS

This large-scale international survey used a harmonised questionnaire. Fourteen countries participated during the period of May-August 2020. Sleep and daytime problems (poor sleep quality, sleep onset and maintenance problems, nightmares, hypnotic use, fatigue and excessive sleepiness) occurring 'before' and 'during' the pandemic were investigated. In total, 25 484 people participated and 22 151 (86.9%) responded to the key parameters and were included. Effects of COVID-19, confinement and financial suffering were considered. In the fully adjusted logistic regression models, results (weighted and stratified by country) were adjusted for gender, age, marital status, educational level, ethnicity, presence of sleep problems before COVID-19 and severity of the COVID-19 pandemic in each country at the time of the survey.

RESULTS

The responders were mostly women (64%) with a mean age 41.8 (SD 15.9) years (median 39, range 18-95). Altogether, 3.0% reported having had COVID-19; 42.2% reported having been in confinement; and 55.9% had suffered financially. All sleep and daytime problems worsened during the pandemic by about 10% or more. Also, some participants reported improvements in sleep and daytime function. For example, sleep quality worsened in about 20% of subjects and improved in about 5%. COVID-19 was particularly associated with poor sleep quality, early morning awakening and daytime sleepiness. Confinement was associated with poor sleep quality, problems falling asleep and decreased use of hypnotics. Financial suffering was associated with all sleep and daytime problems, including nightmares and fatigue, even in the fully adjusted logistic regression models.

CONCLUSIONS

Sleep problems, fatigue and excessive sleepiness increased significantly worldwide during the first phase of the COVID-19 pandemic. Problems were associated with confinement and especially with financial suffering.

摘要

目的

睡眠对人类健康和福祉很重要。以前没有研究评估过 COVID-19 大流行是否会影响全球的睡眠和日间功能。

方法

本大规模国际调查使用了一份协调一致的问卷。2020 年 5 月至 8 月期间,有 14 个国家参与了这项调查。调查了在大流行前和大流行期间出现的睡眠和日间问题(睡眠质量差、入睡和维持睡眠困难、噩梦、使用催眠药、疲劳和过度嗜睡)。共有 25484 人参与,其中 22151 人(86.9%)回答了关键参数并被纳入分析。考虑了 COVID-19、隔离和经济困难的影响。在完全调整的逻辑回归模型中,根据国家加权和分层,结果(根据性别、年龄、婚姻状况、教育水平、种族、COVID-19 前睡眠问题的存在以及调查时每个国家 COVID-19 大流行的严重程度进行调整)。

结果

应答者主要为女性(64%),平均年龄 41.8(15.9)岁(中位数 39,范围 18-95)。共有 3.0%的人报告曾感染 COVID-19;42.2%的人报告被隔离;55.9%的人经济困难。所有睡眠和日间问题在大流行期间恶化了约 10%或更多。此外,一些参与者报告睡眠和日间功能有所改善。例如,约 20%的人的睡眠质量恶化,约 5%的人的睡眠质量改善。COVID-19 与睡眠质量差、清晨早醒和日间嗜睡尤其相关。隔离与睡眠质量差、入睡困难和催眠药使用减少有关。经济困难与所有睡眠和日间问题有关,包括噩梦和疲劳,即使在完全调整的逻辑回归模型中也是如此。

结论

在 COVID-19 大流行的第一阶段,全球范围内的睡眠问题、疲劳和过度嗜睡显著增加。这些问题与隔离,尤其是与经济困难有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e56/8671846/5c5eb4289dd6/bmjopen-2021-050672f01.jpg

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