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新型冠状病毒肺炎对淋巴系统恶性肿瘤的影响。

Effects of COVID-19 in lymphoid malignancies.

作者信息

Özdemir Öner

机构信息

Division of Pediatric Allergy and Immunology, Sakarya University Medical Faculty, Adapazarı 54100, Sakarya, Turkey.

出版信息

World J Virol. 2021 Nov 25;10(6):329-331. doi: 10.5501/wjv.v10.i6.329.

Abstract

I will have a couple of comments on the issues elaborated in the article titled as 'Impact of COVID-19 in patients with lymphoid malignancies'. First, the author did not emphasize and overlook the prolonged persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in coronavirus disease 2019 (COVID-19) patients with hematological malignancies. Second, the rise of a chronic lymphoid leukemia clone in COVID-19 was not mentioned by the authors. Third, achieving a complete remission in asymptomatic COVID-19 patients with follicular lymphoma in partial remission after bendamustine-based therapy is not specific to this lymphoma subtype. Fourth, follicular lymphoma does not always undergo complete remission with SARS-CoV-2 infection. Our aim is to help the authors to discuss and clarify these issues a little more in COVID-19 patients with hematological malignancies.

摘要

对于题为《COVID-19对淋巴系统恶性肿瘤患者的影响》一文中阐述的问题,我有几点看法。首先,作者没有强调且忽略了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)RNA在2019冠状病毒病(COVID-19)血液系统恶性肿瘤患者中持续存在的时间延长这一情况。其次,作者未提及COVID-19中慢性淋巴细胞白血病克隆的出现。第三,在基于苯达莫司汀的治疗后处于部分缓解的滤泡性淋巴瘤无症状COVID-19患者中实现完全缓解并非该淋巴瘤亚型所特有。第四,滤泡性淋巴瘤并非总是因SARS-CoV-2感染而实现完全缓解。我们的目的是帮助作者在COVID-19血液系统恶性肿瘤患者中对这些问题进行更多的讨论和阐明。

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