血液学参数作为猪饲料效率的潜在指标。
Hematology parameters as potential indicators of feed efficiency in pigs.
作者信息
Lindholm-Perry Amanda K, Kuehn Larry A, Wells James E, Rempel Lea A, Chitko-McKown Carol G, Keel Brittney N, Oliver William T
机构信息
USDA, Agricultural Research Service, U.S. Meat Animal Research Center, Clay Center, NE 68933, USA.
出版信息
Transl Anim Sci. 2021 Nov 19;5(4):txab219. doi: 10.1093/tas/txab219. eCollection 2021 Oct.
The identification of an inexpensive, indirect measure of feed efficiency in swine could be a useful tool to help identify animals with improved phenotypes to supplement expensive phenotypes including individual feed intakes. The purpose of this study was to determine whether hematology parameters in pigs at the beginning and end of a feed efficiency study, or changes in those values over the study, were associated with average daily gain (ADG), average daily feed intake (ADFI), or gain-to-feed (G:F). Whole blood samples were taken at days 0 and 42 from pigs ( = 178) that were monitored for individual feed intakes and body weight gain during a 6-week study. Blood samples were analyzed for blood cell parameters including white blood cell (WBC), neutrophil, lymphocyte, monocyte, eosinophil and basophil counts, red blood cell (RBC) counts, hemoglobin, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC), platelet count, and mean platelet volume (MPV). Feed efficiency parameters were predicted using an ANOVA model including fixed effects of farrowing group and pen (sex constant) and individual hematology parameters at day 0, day 42 or their change as covariates. At day 0, platelet count was positively associated with ADFI ( < 0.05) and negatively associated with G:F ( < 0.1), and lymphocyte count was positively associated with ADFI ( < 0.05). At day 42, neutrophil, RBC counts, hemoglobin and hematocrit were associated with ADFI ( < 10). Over the course of the study, changes in RBC measurements including RBC, hemoglobin, MCV, MCH, and MCHC ( < 10) which may improve oxygen carrying capacity, were associated with ADG and ADFI. The change in hematocrit over the course of the study was the only parameter that was associated with all three measures of feed efficiency ( < 0.05). Changes in RBC parameters, especially hematocrit, may be useful measurements to supplement feed efficiency phenotypes in swine.
确定一种低成本的猪饲料效率间接测量方法，可能是一种有用的工具，有助于识别具有改良表型的动物，以补充包括个体采食量在内的昂贵表型。本研究的目的是确定在饲料效率研究开始和结束时猪的血液学参数，或这些值在研究过程中的变化，是否与平均日增重（ADG）、平均日采食量（ADFI）或料重比（G:F）相关。在为期6周的研究中，对178头猪在第0天和第42天采集全血样本，监测其个体采食量和体重增加情况。对血样进行血细胞参数分析，包括白细胞（WBC）、中性粒细胞、淋巴细胞、单核细胞、嗜酸性粒细胞和嗜碱性粒细胞计数、红细胞（RBC）计数、血红蛋白、血细胞比容、平均红细胞体积（MCV）、平均红细胞血红蛋白（MCH）和平均红细胞血红蛋白浓度（MCHC）、血小板计数和平均血小板体积（MPV）。使用方差分析模型预测饲料效率参数，该模型包括产仔组和栏位（性别恒定）的固定效应以及第0天、第42天的个体血液学参数或其变化作为协变量。在第0天，血小板计数与ADFI呈正相关（P<0.05），与G:F呈负相关（P<0.1），淋巴细胞计数与ADFI呈正相关（P<0.05）。在第42天，中性粒细胞、RBC计数、血红蛋白和血细胞比容与ADFI相关（P<0.1）。在研究过程中，RBC测量值的变化包括RBC、血红蛋白、MCV、MCH和MCHC（P<0.1），这些变化可能提高氧携带能力，与ADG和ADFI相关。研究过程中血细胞比容的变化是唯一与所有三种饲料效率指标相关的参数（P<0.05）。RBC参数的变化，尤其是血细胞比容的变化，可能是补充猪饲料效率表型的有用测量指标。
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