数量的力量：肠道微生物组成为焦点。
Power in Numbers: The Gut Microbiome Takes the Spotlight.
机构信息
Faculty of Medicine and Health Sciences, Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec H3G 1Y6, Canada.
出版信息
Chem Res Toxicol. 2022 Feb 21;35(2):112-114. doi: 10.1021/acs.chemrestox.1c00344. Epub 2021 Dec 22.
Abstract
Containing a plethora of microorganisms, the gut microbiome introduces novel metabolic pathways and metabolites that can influence both human health and disease.
摘要
肠道微生物组中含有大量的微生物，这些微生物可以引入新的代谢途径和代谢产物，从而影响人类的健康和疾病。
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本文引用的文献
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Expanding the drug discovery space with predicted metabolite-target interactions.利用预测的代谢物-靶标相互作用拓展药物发现空间。
Commun Biol. 2021 Mar 5;4(1):288. doi: 10.1038/s42003-021-01822-x.
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Sulfamethoxazole drug stress upregulates antioxidant immunomodulatory metabolites in Escherichia coli.磺胺甲恶唑药物应激上调大肠杆菌中的抗氧化免疫调节代谢物。
Nat Microbiol. 2020 Nov;5(11):1319-1329. doi: 10.1038/s41564-020-0763-4. Epub 2020 Jul 27.
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The Microbiome and Its Potential for Pharmacology.微生物组及其药理学潜力。
Handb Exp Pharmacol. 2019;260:301-326. doi: 10.1007/164_2019_317.
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Structural and Functional Analysis of the Gut Microbiome for Toxicologists.毒理学家的肠道微生物群结构与功能分析
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