Gul Aysegul, Gallus Izabela, Tegginamath Akshat, Maryska Jiri, Yalcinkaya Fatma
Institute for Nanomaterials, Advanced Technology and Innovation, Technical University of Liberec, Studentska 1402/2, 46117 Liberec, Czech Republic.
Faculty of Mechatronics, Informatics and Interdisciplinary Studies, Technical University of Liberec, Studentska 1402/2, 46117 Liberec, Czech Republic.
Membranes (Basel). 2021 Nov 23;11(12):908. doi: 10.3390/membranes11120908.
Chronic wounds are caused by bacterial infections and create major healthcare discomforts; to overcome this issue, wound dressings with antibacterial properties are to be utilized. The requirements of antibacterial wound dressings cannot be fulfilled by traditional wound dressing materials. Hence, to improve and accelerate the process of wound healing, an antibacterial wound dressing is to be designed. Electrospun nanofibers offer a promising solution to the management of wound healing, and numerous options are available to load antibacterial compounds onto the nanofiber webs. This review gives us an overview of some recent advances of electrospun antibacterial nanomaterials used in wound dressings. First, we provide a brief overview of the electrospinning process of nanofibers in wound healing and later discuss electrospun fibers that have incorporated various antimicrobial agents to be used in wound dressings. In addition, we highlight the latest research and patents related to electrospun nanofibers in wound dressing. This review also aims to concentrate on the importance of nanofibers for wound dressing applications and discuss functionalized antibacterial nanofibers in wound dressing.
慢性伤口由细菌感染引起，会给医疗保健带来极大不便；为克服这一问题，需使用具有抗菌特性的伤口敷料。传统伤口敷料材料无法满足抗菌伤口敷料的要求。因此，为改善和加速伤口愈合过程，需设计一种抗菌伤口敷料。电纺纳米纤维为伤口愈合管理提供了一种有前景的解决方案，并且有多种方法可将抗菌化合物负载到纳米纤维网上。本文综述概述了用于伤口敷料的电纺抗菌纳米材料的一些最新进展。首先，我们简要概述纳米纤维在伤口愈合中的电纺过程，随后讨论已掺入各种抗菌剂用于伤口敷料的电纺纤维。此外，我们重点介绍与伤口敷料中电纺纳米纤维相关的最新研究和专利。本文综述还旨在关注纳米纤维在伤口敷料应用中的重要性，并讨论伤口敷料中的功能化抗菌纳米纤维。
