Adult Spine Orthopaedics Department, Poznan University of Medical Sciences, 61545 Poznan, Poland.
Division of Magnetic Resonance Imaging, Silesian Center for Heart Diseases, 41800 Zabrze, Poland.
Medicina (Kaunas). 2021 Nov 30;57(12):1311. doi: 10.3390/medicina57121311.
: The course of SARS-CoV-2 (COVID-19) is still under analysis. The majority of complications arising from the infection are related to the respiratory system. The adverse effect of the viral infection on bone and joint tissue has also been observed. : We present a group of 10 patients with degeneration of large joints and adjacent epiphyses of long bones and the spine, with a background of bone infarctions and avascular necrosis (AVN) immediately after infection with the COVID-19 virus. In MR imaging, changes in the characteristics of AVN were documented. Observation of this group showed a clear correlation among the history of COVID-19 disease in the patients, moderately severe symptoms, high levels of IgG antibodies, and the time of occurrence of joint changes. No other clinically significant complications were observed following COVID-19 infection in the study group. No other risk factors for AVN or autoimmune or degenerative diseases were found in the study group. The group of patients responded well to empirical treatment with steroids, which normalized acute inflammatory symptoms and pain in the joints. During coronavirus (COVID-19) infection, there are complications in the locomotor system, such as microembolism and the formation of AVN; hence, more research is needed.
: SARS-CoV-2（COVID-19）的病程仍在分析中。感染引起的大多数并发症与呼吸系统有关。病毒感染对骨骼和关节组织的不良影响也已经观察到。: 我们报告了一组 10 名患者，他们在感染 COVID-19 病毒后立即出现大关节和长骨及脊柱相邻骨骺的退变，伴有骨梗死和骨坏死（AVN）。在磁共振成像（MR）中，记录了 AVN 特征的变化。对该组的观察表明，患者的 COVID-19 病史、中度严重症状、高 IgG 抗体水平以及关节变化发生时间之间存在明确的相关性。在研究组中，COVID-19 感染后没有观察到其他临床上显著的并发症。在研究组中没有发现其他 AVN 或自身免疫或退行性疾病的风险因素。该组患者对类固醇的经验性治疗反应良好，急性炎症症状和关节疼痛得到缓解。: 在冠状病毒（COVID-19）感染期间，存在运动系统并发症，如微栓塞和 AVN 的形成；因此，需要进一步研究。
