Wang Hongxia, Shao Guangqiang, Zhang Keke
Respiratory and Critical Care Medicine, Department of Surgery, The University of Hong Kong-Shenzhen Hospital Shenzhen 518000, Guangdong, China.
Division of Thoracic Surgery, Department of Surgery, The University of Hong Kong-Shenzhen Hospital Shenzhen 518000, Guangdong, China.
Am J Transl Res. 2021 Nov 15;13(11):12897-12904. eCollection 2021.
To compare the differences between two groups of patients with confirmed and suspected COVID-19.
We retrospectively collected and analyzed the data of confirmed and suspected patients, including demographic, epidemic, laboratory, clinical, radiologic, and treatment data, at the fever clinic and isolation ward of our hospital from December 1, 2019 to December 30, 2019.
The study included 73 patients with confirmed or suspected COVID-19. The median age was 43.6 years old, and 41 patients (56.2%) were male. Patients in the suspected group (SG) (n=47) were significantly older than those in the confirmed group (CG) (n=26). Among 73 patients, 18 (24.6%) had comorbidities. Most laboratory test results in this study were normal, except for total lymphocyte counts and C-reactive protein levels. Patients in the CG had fewer lymphocyte count abnormalities than those of the SG. More patients in the CG (13 cases, 50%) displayed involvement of three or more lobes than those in the SG (8 cases, 17%). More patients in the SG (36 cases, 76.6%) displayed involvement of 1-2 lobes than those in the CG (12 cases, 46.2%). In the CG, computed tomography (CT) lung lesions were mainly distributed in the left lower lung lobe (65.4%) and left upper lung lobe (80.8%).
The reference standard for detecting COVID-19 is still RT-PCR. However, characteristic chest CT results and a history of close contact strongly suggest COVID-19 infection.
比较两组新型冠状病毒肺炎确诊患者和疑似患者之间的差异。
我们回顾性收集并分析了2019年12月1日至2019年12月30日期间我院发热门诊和隔离病房确诊和疑似患者的数据，包括人口统计学、流行病学、实验室、临床、影像学和治疗数据。
该研究纳入了73例新型冠状病毒肺炎确诊或疑似患者。中位年龄为43.6岁，41例（56.2%）为男性。疑似组（SG）（n=47）患者的年龄显著大于确诊组（CG）（n=26）患者。73例患者中，18例（24.6%）有合并症。本研究中大多数实验室检查结果正常，但淋巴细胞总数和C反应蛋白水平除外。CG组患者淋巴细胞计数异常的情况少于SG组。CG组中更多患者（13例，50%）出现三个或更多肺叶受累，而SG组为8例（17%）。SG组中更多患者（36例，76.6%）出现1-2个肺叶受累，而CG组为12例（46.2%）。在CG组中，计算机断层扫描（CT）肺部病变主要分布在左下肺叶（65.4%）和左上肺叶（80.8%）。
检测新型冠状病毒肺炎的参考标准仍然是逆转录聚合酶链反应（RT-PCR）。然而，胸部CT特征性结果和密切接触史强烈提示新型冠状病毒肺炎感染。
