Zhang Sheng, Zeng Junyan, Wang Chunge, Feng Luying, Song Zening, Zhao Wenjie, Wang Qianqian, Liu Chen
State Key Laboratory of Fluid Power and Mechatronic Systems, School of Mechanical Engineering, Ningbo Research Institute, Zhejiang University, Hangzhou, China.
School of Mechanical and Energy Engineering, Ningbo Tech University, Ningbo, China.
Front Bioeng Biotechnol. 2021 Dec 8;9:774210. doi: 10.3389/fbioe.2021.774210. eCollection 2021.
Diabetes and its complications have become a worldwide concern that influences human health negatively and even leads to death. The real-time and convenient glucose detection in biofluids is urgently needed. Traditional glucose testing is detecting glucose in blood and is invasive, which cannot be continuous and results in discomfort for the users. Consequently, wearable glucose sensors toward continuous point-of-care glucose testing in biofluids have attracted great attention, and the trend of glucose testing is from invasive to non-invasive. In this review, the wearable point-of-care glucose sensors for the detection of different biofluids including blood, sweat, saliva, tears, and interstitial fluid are discussed, and the future trend of development is prospected.
糖尿病及其并发症已成为一个全球关注的问题,对人类健康产生负面影响,甚至导致死亡。生物流体中实时且便捷的葡萄糖检测迫切需要。传统的葡萄糖检测是检测血液中的葡萄糖,具有侵入性,无法连续进行,给使用者带来不适。因此,用于生物流体中连续即时葡萄糖检测的可穿戴葡萄糖传感器备受关注,葡萄糖检测的趋势正从侵入性向非侵入性发展。在这篇综述中,讨论了用于检测包括血液、汗液、唾液、眼泪和组织液等不同生物流体的可穿戴即时葡萄糖传感器,并展望了未来的发展趋势。