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本文引用的文献

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Retinal findings in hospitalised patients with severe COVID-19.住院严重 COVID-19 患者的视网膜表现。
Br J Ophthalmol. 2022 Jan;106(1):102-105. doi: 10.1136/bjophthalmol-2020-317576. Epub 2020 Oct 16.
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Retinal findings in patients with COVID-19: Results from the SERPICO-19 study.新型冠状病毒肺炎患者的视网膜表现:SERPICO-19研究结果
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Impending Central Retinal Vein Occlusion in a Patient with Coronavirus Disease 2019 (COVID-19).COVID-19 相关的中央视网膜静脉阻塞。
Ocul Immunol Inflamm. 2020 Nov 16;28(8):1290-1292. doi: 10.1080/09273948.2020.1807023. Epub 2020 Sep 25.
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Excess mortality: the gold standard in measuring the impact of COVID-19 worldwide?超额死亡率:衡量新冠疫情对全球影响的金标准?
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A comprehensive review of COVID-19 characteristics.对新冠病毒特性的全面综述。
Biol Proced Online. 2020 Aug 4;22:19. doi: 10.1186/s12575-020-00128-2. eCollection 2020.
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Papillophlebitis in a COVID-19 patient: Inflammation and hypercoagulable state.COVID-19 患者的乳头静脉炎:炎症和高凝状态。
Eur J Ophthalmol. 2022 Jan;32(1):NP168-NP172. doi: 10.1177/1120672120947591. Epub 2020 Jul 30.
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Emerging evidence of a COVID-19 thrombotic syndrome has treatment implications.越来越多的证据表明 COVID-19 存在血栓综合征,这对治疗有影响。
Nat Rev Rheumatol. 2020 Oct;16(10):581-589. doi: 10.1038/s41584-020-0474-5. Epub 2020 Jul 30.
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Acute ophthalmic artery occlusion in a COVID-19 patient on apixaban.COVID-19 患者在服用阿哌沙班后发生急性眼动脉阻塞。
J Stroke Cerebrovasc Dis. 2020 Aug;29(8):104982. doi: 10.1016/j.jstrokecerebrovasdis.2020.104982. Epub 2020 May 23.
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Paracentral acute middle maculopathy and acute macular neuroretinopathy following SARS-CoV-2 infection.新型冠状病毒感染后的中心旁急性黄斑病变和急性黄斑神经视网膜病变
Eye (Lond). 2020 Dec;34(12):2352-2353. doi: 10.1038/s41433-020-1069-8. Epub 2020 Jul 3.
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Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020.估算 2020 年 3 月至 5 月美国 COVID-19 大流行期间的超额死亡人数。
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新冠疫情期间视网膜动脉和静脉阻塞的发生率。

Incidence of Retinal Artery and Vein Occlusions During the COVID-19 Pandemic.

出版信息

Ophthalmic Surg Lasers Imaging Retina. 2022 Jan;53(1):22-30. doi: 10.3928/23258160-20211209-01. Epub 2022 Jan 1.

DOI:10.3928/23258160-20211209-01
PMID:34982005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10699281/
Abstract

BACKGROUND AND OBJECTIVE

To examine whether new cases of retinal artery occlusion (RAO) or retinal vein occlusion (RVO) increased during the coronavirus 209 (COVID-19) pandemic.

PATIENTS AND METHODS

This was a retrospective cohort study of patients visiting retina clinics with a new diagnosis in two time periods: between January 1, 2019, and February 29, 2020 (the pre-COVID-19 period), and between March 1, 2020, and December 31, 2020 (the COVID-19 period). The key outcome was the percentage of newly diagnosed central RAO (CRAO), branch RAO (BRAO), central RVO (CRVO), and branch RVO (BRVO) seen in each period.

RESULTS

The study population included 285,759 new patients in the pre-COVID-19 period and 156,427 new patients in the COVID-19 period. The overall number of new patients dropped dramatically during the first few months of the COVID-19 pandemic (24%, 66%, and 51% less new patients in March, April, and May 2020 than in the same months in 2019; < .0001 for all 3 months). However, the decrease in the number of newly diagnosed patients with CRAO, CRVO, and BRAO during these months was less dramatic. As most states reopened in June and the number of patients in retina clinics started to increase, the newly diagnosed patients with these conditions as a percentage of all new diagnoses returned to similar trends as seen in the pre-COVID-19 period.

CONCLUSIONS

The percentage of new cases of RAO and RVO with respect to all new diagnoses in retina clinics remained stable for the majority of the COVID-19 period. There was an increase in these percentages during the first few months of the COVID-19 pandemic, particularly for CRAO, CRVO, and BRAO, which may have led to the presumption that more patients presented with these conditions during the COVID-19 period evaluated in this study.

摘要

背景与目的

研究新冠病毒 2019(COVID-19)大流行期间是否新出现视网膜动脉阻塞(RAO)或视网膜静脉阻塞(RVO)病例。

患者与方法

这是一项回顾性队列研究,纳入于两个时间段在视网膜诊所就诊且诊断为新发疾病的患者:2019 年 1 月 1 日至 2 月 29 日(COVID-19 前时期)和 2020 年 3 月 1 日至 12 月 31 日(COVID-19 时期)。主要结局是观察每个时期新诊断为中央性视网膜动脉阻塞(CRAO)、分支性视网膜动脉阻塞(BRAO)、中央性视网膜静脉阻塞(CRVO)和分支性视网膜静脉阻塞(BRVO)的新病例比例。

结果

研究人群包括 COVID-19 前时期的 285759 例新患者和 COVID-19 时期的 156427 例新患者。在 COVID-19 大流行的最初几个月中,新患者总数急剧下降(2020 年 3、4 和 5 月新患者比 2019 年同期分别减少 24%、66%和 51%;所有 3 个月均 <.0001)。然而,这些月份新诊断的 CRAO、CRVO 和 BRAO 患者数量减少的幅度较小。随着大多数州在 6 月重新开放,视网膜诊所的患者数量开始增加,这些疾病的新诊断患者占所有新诊断患者的比例恢复到 COVID-19 前时期的类似趋势。

结论

COVID-19 大流行期间,视网膜诊所新诊断的 RAO 和 RVO 病例占所有新诊断病例的比例保持稳定。在 COVID-19 大流行的最初几个月中,这些比例有所增加,尤其是 CRAO、CRVO 和 BRAO,这可能导致人们认为在本研究评估的 COVID-19 期间出现这些疾病的患者更多。