Discipline of Optometry, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Int Ophthalmol. 2022 Jun;42(6):1697-1709. doi: 10.1007/s10792-021-02164-7. Epub 2022 Jan 5.
Assessment of anterior chamber angle (ACA) variables is important to screen, diagnose and monitor ocular anomalies. Even though data on ACA variables, such as angle-opening distance taken at 500 µm (AOD500) and trabecular-iris angle (TIA), are available in the literature, limited information is available about these variables in African sub-populations. The purpose of this study is to describe the distribution of ACA measurements (AOD500 and TIA) in a South African young adult population.
In this cross-sectional study, 700 young adults were recruited from a university student population using two-stage random sampling. The Optovue iVue 100 optical coherence tomographer was used to measure the ACA variables. The distribution of the AOD500 and TIA measurements was analysed using descriptive and inferential statistics. Data from only the right eyes were analysed because the ACA measurements in the two eyes showed high levels of interocular symmetry.
The measurements for the nasal and temporal ACAs were asymmetrically distributed (p < 0.001). The median AOD500 measurements in the nasal and temporal angles were 539 µm and 542 µm, respectively. The median TIA measurements were similar (~ 36°) in the two horizontal angles. The temporal ACA measurements were slightly higher than the nasal ACA measurements. Females had higher median ACA measurements than males (p ≥ 0.029).
The ACA measurements in South African young adults resemble non-Gaussian curves. The ACA measurements are different from that reported in other sub-populations worldwide and most participants had ACA measurements associated with non-occludable ACAs.
评估前房角（ACA）变量对于筛选、诊断和监测眼部异常非常重要。尽管文献中已有关于ACA 变量的数据，如 500µm 处的巩膜突宽度（AOD500）和小梁虹膜角度（TIA），但在非洲亚人群中，这些变量的信息有限。本研究的目的是描述南非年轻成年人人群的 ACA 测量值（AOD500 和 TIA）分布。
在这项横断面研究中，使用两阶段随机抽样法从大学生群体中招募了 700 名年轻人。使用 Optovue iVue 100 光学相干断层扫描仪测量 ACA 变量。使用描述性和推断性统计方法分析 AOD500 和 TIA 测量值的分布。由于双眼 ACA 测量值具有高度的眼间对称性，因此仅分析右眼的数据。
鼻侧和颞侧 ACA 的测量值呈不对称分布（p<0.001）。鼻侧和颞侧 ACA 的中位数 AOD500 测量值分别为 539µm 和 542µm。两个水平角度的中位数 TIA 测量值相似（~36°）。颞侧 ACA 测量值略高于鼻侧 ACA 测量值。女性的 ACA 测量值中位数高于男性（p≥0.029）。
南非年轻成年人的 ACA 测量值与非正态曲线相似。ACA 测量值与全球其他亚人群报告的测量值不同，大多数参与者的 ACA 测量值与非闭角型 ACA 相关。
