Department of Psychology, University of Oregon, Eugene, OR 97403, USA.
Oregon Research Institute, Eugene, OR, USA.
Soc Cogn Affect Neurosci. 2022 Aug 1;17(8):744-755. doi: 10.1093/scan/nsac001.
Depression affects neural processing of emotional stimuli and could, therefore, impact parent-child interactions. However, the neural processes with which mothers with depression process their adolescents' affective interpersonal signals and how this relates to mothers' parenting behavior are poorly understood. Mothers with and without depression (N = 64 and N = 51, respectively; Mage = 40 years) from low-income families completed an interaction task with their adolescents (Mage = 12.8 years), which was coded for both individuals' aggressive, dysphoric, positive and neutral affective behavior. While undergoing fMRI, mothers viewed video clips from this task of affective behavior from their own and an unfamiliar adolescent. Relative to non-depressed mothers, those with depression showed more aggressive and less positive affective behavior during the interaction task and more activation in the bilateral insula, superior temporal gyrus and striatum but less in the lateral prefrontal cortex while viewing aggressive and neutral affect. Findings were comparable for own and unfamiliar adolescents' affect. Heightened limbic, striatal and sensory responses were associated with more aggressive and dysphoric parenting behavior during the interactions, while reduced lateral prefrontal activation was associated with less positive parenting behavior. These results highlight the importance of depressed mothers' affective information processing for understanding mothers' behavior during interactions with their adolescents.
抑郁会影响情绪刺激的神经处理，因此可能会影响亲子互动。然而，患有抑郁症的母亲如何处理其青少年的情感人际信号，以及这与母亲的育儿行为有何关联，目前人们对此知之甚少。来自低收入家庭的有和没有抑郁症的母亲（分别为 N=64 和 N=51，Mage=40 岁）与他们的青少年（Mage=12.8 岁）完成了一项互动任务，该任务对双方的攻击、抑郁、积极和中性的情感行为进行了编码。在进行 fMRI 扫描时，母亲观看了来自任务中自己和不熟悉的青少年的情感行为的视频片段。与非抑郁母亲相比，患有抑郁症的母亲在互动任务中表现出更多的攻击性行为和更少的积极情感，而在观看攻击性行为和中性情绪时，双侧脑岛、颞上回和纹状体的活跃度更高，而外侧前额叶皮层的活跃度较低。对于自己和不熟悉的青少年的情感，发现结果是相似的。在互动过程中，边缘、纹状体和感觉反应增强与更具攻击性和更抑郁的育儿行为有关，而外侧前额叶皮层的激活减少与积极育儿行为减少有关。这些结果强调了抑郁母亲情感信息处理对理解母亲与青少年互动时行为的重要性。
