Department of Anatomy, Bayero University Kano, Kano, Nigeria.
Department of Physiology, Bayero University Kano, Kano, Nigeria.
Front Public Health. 2021 Dec 23;9:762429. doi: 10.3389/fpubh.2021.762429. eCollection 2021.
Prediabetes is a borderline glycemic status associated with both higher incidence of cardiovascular disease as well as higher risk of progression to diabetes. There is a rising burden of diabetes and prediabetes globally. This study aims to estimate the burden of prediabetes in Nigeria. Online searches of Google Scholar, PubMed, and Scopus were conducted and studies were selected based on predefined criteria. A total of 15 studies consisting of 14,206 individuals conducted between 2000 and 2019 were included in the meta-analysis with studies using American Diabetic Association (ADA) and World Health Organization (WHO) criteria pooled separately. The pooled prevalence of prediabetes in Nigeria was found to be 13.2% (95% CI: 5.6-23.2%, = 98.4%) using the ADA criteria and 10.4% (95% CI: 4.3-18.9%, = 99.2%) using the WHO criteria. According to the latest data by the United Nations, this translates to an estimated 15.8 and 12.5 million adult prediabetic individuals in Nigeria using the ADA and WHO criteria, respectively. The prevalence rates for women and men were similar at 12.1% (95% CI: 5-21%). The pooled prevalence rates for urban and rural settlements were also similar at 9% (95% CI: 2-22%). In conclusion, the prevalence of prediabetes in Nigeria was almost two times higher than the 7.3% estimate by the International Diabetes Federation in 2003. The similar rates of prediabetes between men and women and between urban and rural settlements points toward narrowing of cardiovascular risk burden between the two sexes and the two settlements. This represents higher future cardiovascular disease burden in the country further pressurizing the overstretched healthcare system.
糖尿病前期是一种血糖边缘状态，与心血管疾病发生率增加以及向糖尿病进展的风险增加有关。全球糖尿病和糖尿病前期的负担不断增加。本研究旨在估计尼日利亚糖尿病前期的负担。在线搜索了 Google Scholar、PubMed 和 Scopus，并根据预先确定的标准选择了研究。共有 15 项研究，包括 2000 年至 2019 年间进行的 14206 名个体，使用美国糖尿病协会 (ADA) 和世界卫生组织 (WHO) 标准分别进行了荟萃分析。使用 ADA 标准，尼日利亚糖尿病前期的总患病率为 13.2%（95%CI：5.6-23.2%， = 98.4%），使用 WHO 标准为 10.4%（95%CI：4.3-18.9%， = 99.2%）。根据联合国的最新数据，这意味着使用 ADA 和 WHO 标准，尼日利亚分别有估计 1580 万和 1250 万成年糖尿病前期患者。女性和男性的患病率相似，为 12.1%（95%CI：5-21%）。城乡居民的患病率也相似，为 9%（95%CI：2-22%）。总之，尼日利亚糖尿病前期的患病率几乎是国际糖尿病联合会 2003 年估计的 7.3%的两倍。男性和女性以及城乡居民之间相似的糖尿病前期患病率表明，两性和城乡之间的心血管风险负担正在缩小。这意味着该国未来的心血管疾病负担更高，进一步给已经紧张的医疗保健系统带来压力。
