正畸牙移动过程中龈沟液中的瘦素水平
Leptin Levels in Gingival Crevicular Fluid during Orthodontic Tooth Movement.
作者信息
Alaguselvaraj Joseph, Selvaraj Kandanraj, Bhaskaran Porselvi, Chidambaram Sainath Muthiah, Rajasekaran Thanigainathan, Mani Muralimani
机构信息
Department of Dental Surgery, Madurai Medical College, Madurai, Tamil Nadu, India.
Department of Orthodontia, Madha Dental College and Hospital, Chennai, Tamil Nadu, India.
出版信息
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1174-S1177. doi: 10.4103/jpbs.jpbs_285_21. Epub 2021 Nov 10.
AIM
To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement.
MATERIALS AND METHODS
GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E).
RESULTS
GCF Leptin concentration in pretreatment, 6 h control and 21 day control were all similar. GCF leptin concentration at 6 h test tooth site was increased which was statistically significant. GCF leptin concentration in 21 day test tooth was decreased only a little than the control tooth which shows statistically no difference.
CONCLUSION
Leptin is one of the mediators of orthodontic tooth movement.
目的
评估正畸牙齿移动过程中龈沟液（GCF）中瘦素的水平，并探讨瘦素作为牙齿移动介质的作用。
材料与方法
收集25名受试者的龈沟液并测量其中瘦素的水平。样本（A）预处理，（B）从右侧尖牙施加正畸牵引力6小时后，（C）左侧尖牙未施加牵引力，右侧尖牙21天后（D），以及左侧尖牙（E）。
结果
预处理、6小时对照和21天对照时龈沟液瘦素浓度均相似。试验牙部位6小时时龈沟液瘦素浓度升高，具有统计学意义。21天时试验牙的龈沟液瘦素浓度仅比对照牙略有降低，统计学上无差异。
结论
瘦素是正畸牙齿移动的介质之一。
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