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种植体表面抗菌技术的分类及研究进展

Classification and research progress of implant surface antimicrobial techniques.

作者信息

Zheng Tian-Xia, Li Wen, Gu Ying-Ying, Zhao Di, Qi Meng-Chun

机构信息

Department of Oral & Maxillofacial Surgery, College of Stomatology, North China University of Science and Technology, Tangshan City, Hebei Province, PR China.

出版信息

J Dent Sci. 2022 Jan;17(1):1-7. doi: 10.1016/j.jds.2021.08.019. Epub 2021 Sep 20.

Abstract

Due to the good biocompatibility and ideal mechanical property, titanium implants have been widely used in dental clinic and orthopedic surgery. However, bacteria induced infection can cause per-implant inflammation and decrease the success rate of implant surgery. Therefore, developing antimicrobial techniques is essential to successful application of titanium implants. Many surface antimicrobial techniques, including antimicrobial coating and surface modifications, have been explored and they always exert antimicrobial effect by reducing bacterial adhesion, inhibiting their metabolism, or destructing cell structure. In this paper, different surface antimicrobial techniques and their recent research progress are reviewed to provide a brief insight on this area.

摘要

由于具有良好的生物相容性和理想的机械性能,钛植入物已广泛应用于牙科临床和整形外科手术。然而,细菌诱导的感染会导致种植体周围炎症,并降低种植手术的成功率。因此,开发抗菌技术对于钛植入物的成功应用至关重要。许多表面抗菌技术,包括抗菌涂层和表面改性,已经被探索,它们总是通过减少细菌粘附、抑制其代谢或破坏细胞结构来发挥抗菌作用。本文综述了不同的表面抗菌技术及其最新研究进展,以提供对该领域的简要见解。

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本文引用的文献

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Zn-doped mesoporous hydroxyapatites and their antimicrobial properties.锌掺杂介孔羟基磷灰石及其抗菌性能。
Colloids Surf B Biointerfaces. 2021 Feb;198:111471. doi: 10.1016/j.colsurfb.2020.111471. Epub 2020 Nov 16.
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