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男性乳腺癌的临床病理及预后因素评估:单中心经验

Evaluation of Clinicopathological and Prognostic Factors of Male Breast Cancer: A Single-Centre Experience.

作者信息

Das Majumdar Saroj Kumar, Das Deepak K, Barik Sandip, Badajena Avinash, Parida Dillip Kumar

机构信息

Radiation Oncology, All India Institute of Medical Sciences, Bhubaneswar, IND.

出版信息

Cureus. 2021 Dec 9;13(12):e20298. doi: 10.7759/cureus.20298. eCollection 2021 Dec.

Abstract

Male breast cancer (MBC) is a rare malignancy with an overall incidence of less than 1%. The epidemiological data of MBC is very limited owing to its rarity, particularly data from India. Hence, it is important to study different aspects of this rare malignancy. This paper reports a single-center experience from India that evaluated the clinicopathological behavior of MBC, their management, and outcomes. This was a retrospective review, which included 18 patients managed between 2013 to 2021. Seventeen out of the 18 patients were aged ≥50 years; the median age was 60 years. Left sides were affected more than right (left: 11, right: seven), and the most commonly affected quadrant was central (n=15/17, 88.2%). The most common (n=14) surgery was modified radical mastectomy (MRM), and the invasive ductal carcinoma was the most common (n=14) histological finding. Most cases were estrogen-receptor (ER) and progesterone-receptor-positive (n=15/18, 83.3%). The present study, though with a small sample size, adds valuable information to the literature about this rare occurrence in men.

摘要

男性乳腺癌(MBC)是一种罕见的恶性肿瘤,总体发病率低于1%。由于其罕见性,MBC的流行病学数据非常有限,尤其是来自印度的数据。因此,研究这种罕见恶性肿瘤的不同方面很重要。本文报告了一项来自印度的单中心经验,该经验评估了MBC的临床病理行为、治疗方法及治疗结果。这是一项回顾性研究,纳入了2013年至2021年间接受治疗的18例患者。18例患者中有17例年龄≥50岁;中位年龄为60岁。左侧受累多于右侧(左侧:11例,右侧:7例),最常受累的象限是中央象限(n=15/17,88.2%)。最常见的手术(n=14)是改良根治性乳房切除术(MRM),最常见的组织学发现是浸润性导管癌(n=14)。大多数病例雌激素受体(ER)和孕激素受体呈阳性(n=15/18,83.3%)。本研究虽然样本量较小,但为关于男性这种罕见疾病的文献增添了有价值的信息。

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