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腹内侧下丘脑损伤大鼠的肥胖、暴饮暴食和胃排空加快

Obesity, overeating, and rapid gastric emptying in rats with ventromedial hypothalamic lesions.

作者信息

Duggan J P, Booth D A

出版信息

Science. 1986 Feb 7;231(4738):609-11. doi: 10.1126/science.3511527.

DOI:10.1126/science.3511527
PMID:3511527
Abstract

Measurements confirm the quantitative theoretical prediction that the autonomic nonendocrine abnormality of rapid daytime gastric emptying is the major primary cause of the obesity resulting from ventromedial hypothalamic lesions in rats. Therapy for obesity could include slowing of stomach emptying.

摘要

测量结果证实了定量理论预测，即大鼠腹内侧下丘脑损伤所致肥胖的主要原发性原因是白天胃排空迅速这一自主神经非内分泌异常。肥胖治疗可包括减缓胃排空。

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