Gomez Urcuyo F, Zaias N
Int J Dermatol. 1986 Jan-Feb;25(1):60-2. doi: 10.1111/j.1365-4362.1986.tb03408.x.
A lotion containing 0.5% malathion was compared with its vehicle (control) in a double-blind, parallel-group study of 119 patients with head louse infestations confirmed by live ova in the hair. The lotions remained in place for 8 hours. The test preparation was superior to the control lotion by a highly significant margin (p less than 0.001) as determined by the numbers of patients with live lice at 24 hours and 7 days after removal of the respective materials. It also proved superior to the vehicle (p less than 0.001) as an ovicidal agent, judged by comparative differences in hatching rates between nits collected and incubated before treatment and those obtained and incubated after treatment. No adverse reaction occurred.
在一项针对119名头虱感染患者的双盲平行组研究中，将含有0.5%马拉硫磷的洗剂与其赋形剂（对照）进行了比较。这些患者的头发中经活卵确诊为头虱感染。洗剂保留8小时。根据去除相应材料后24小时和7天时仍有活虱的患者数量判断，试验制剂比对照洗剂具有极显著优势（p<0.001）。通过比较治疗前收集并孵化的虱卵与治疗后获得并孵化的虱卵的孵化率差异判断，作为杀卵剂，它也优于赋形剂（p<0.001）。未发生不良反应。
